Evidence map›Paper›PMID 41973604›Full record

ReviewThe MAK collection for occupational health and safety2025

2-Mercaptobenzothiazole: MAK Value Documentation, addendum - Translation of the German version from 2022.

Andrea Hartwig, MAK Commission

Abstract readReview
In one paragraph

Review in The MAK collection for occupational health and safety, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Toluene: MAK Value Documentation, addendum - Translation of the German version from 2021.The MAK collection for occupational health and safety · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Andrea HartwigInstitute of Applied Biosciences. Department of Food Chemistry and Toxicology. Karlsruhe Institute of Technology (KIT) Adenauerring 20a, Building 50.41 76131 Karlsruhe Germany.
MAK Commission

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area (MAK Commission) has summarized and re-evaluated the data for 2-mercaptobenzothiazole [149-30-4] considering all toxicological end points. Relevant studies were identified from a literature search and also unpublished study reports were used. The critical effect in humans and animals is sensitization. Data for chronic inhalation exposure are not available. The most sensitive systemic end point observed in a 13-week gavage study in rats was an increase in relative liver weights. The female rat was found to be the most sensitive species. A LOAEL of 188 mg/kg body weight and day was derived, which corresponds to a concentration in the air of 27.5 mg/m

Indexed as

2-mercaptobenzothiazolecarcinogenicityepidemiologyliver weightsensitizationskin absorptiontoxicity

Identifiers

PMID41973604
PMCPMC12820630

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.