Evidence map›Paper›PMID 41973315›Full record

ArticleAging clinical and experimental research2026

Independent and joint associations of psychological resilience and social support with cognitive impairment among middle-aged and older Chinese adults.

Xiaoxia Wei, Fangqin Tan, Weihao Shao, Ji Zhang, Yihao Zhao, Yue Zhang, Jean-Pierre Michel, Enying Gong, Philipe de Souto Barreto, Ruitai Shao

Abstract read
In one paragraph

Article in Aging clinical and experimental research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Xiaoxia WeiSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, China.
Fangqin TanSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, China.
Weihao ShaoSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, China.
Ji ZhangSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, China.
Yihao ZhaoSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, China.
Yue ZhangSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, China.
Jean-Pierre MichelUniversity of Geneva, Geneva, Switzerland.
Enying GongSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, China.
Philipe de Souto BarretoIHU HealthAge, Toulouse, France. philipebarreto81@yahoo.com.br.
Ruitai ShaoSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, China. shaoruitai@cams.cn.

Funding

Chinese Academy of Engineering 2024-GJ-04the CAMS Innovation Fund for Medical Sciences(ClFMS) 2023-I2M-2-001the Disciplines Construction Project:Population Medicine WH10022022010the non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences 2021-RC330-004the non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences 2022-ZHCH330-01
6 · The paper itself

Abstract

backgroundCognitive impairment poses a major public health concern in ageing societies. This study investigated the independent and joint associations of resilience and social support with cognitive function among community-dwelling middle-aged and older Chinese adults, and explored gender-specific differences.

methodsA total of 3,058 Chinese adults aged ≥ 50 years from both urban and rural communities were included. Cognitive function was evaluated using the Mini-Mental State Examination (MMSE). Resilience was assessed using the 10-item Connor-Davidson Resilience Scale (CD-RISC-10), and social support by the 6-item Lubben Social Network Scale (LSNS-6). Logistic regression models stratified by gender were applied with adjustment for demographic, behavioral, and health-related variables. Generalized additive models were used to test non-linear associations, and joint effects were examined with combined categories.

resultsOverall, 18.4% of participants (20.1% women, 16.3% men) had cognitive impairment. Higher resilience and social support were independently associated with lower odds of cognitive impairment, with some variation in effect strength across sex, age group, and educational attainment in sensitivity and stratified analyses. Curvilinear associations were observed in generalized additive models. Compared with low resilience and low support, participants with moderate resilience and high support had the lowest risk (OR = 0.25, 95% CI: 0.11-0.51).

conclusionsResilience and social support were independently and jointly associated with cognitive function among middle-aged and older adults. These associations appeared to be stronger in women, although variation by sex was observed. Given the cross-sectional design, the findings should be interpreted as exploratory, and further longitudinal and interventional studies are needed to clarify the role of psychosocial resources in cognitive ageing.

Indexed as

Cognitive DysfunctionResilience, PsychologicalSocial SupportAgedAged, 80 and overChinaCognitionCross-Sectional StudiesEast Asian PeopleFemaleHumansMaleMiddle AgedCognitive functionCognitive impairmentJoint associationPsychological resiliencePsychosocial factorsSocial support

Identifiers

PMID41973315
PMCPMC13194204

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.