Evidence map›Paper›PMID 41973274›Full record

ArticleEJNMMI physics2026

Contrast-enhanced CT for attenuation correction in ultra-high sensitivity long-axial field-of-view lymphoma PET: amplified quantification problems?

Jan-Luca Penner, August Blomgren, Alexander Weissensee, Michelle Amon, Shayan Acikgöz, Clemens Mingels, Justin Ferdinandus, Foroud Aghapour Zangeneh, Urban Novak, Thomas Pabst and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJNMMI physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jan-Luca Penner *Department of Nuclear Medicine, University Hospital Bern, Inselspital, University of Bern, Rosenbühlgasse 25/27, CH-3010 , Bern, Switzerland. jan-luca.penner@insel.ch.ORCID http://orcid.org/0009-0005-3620-4384
August Blomgren *Department of Nuclear Medicine, University Hospital Bern, Inselspital, University of Bern, Rosenbühlgasse 25/27, CH-3010 , Bern, Switzerland.
Alexander WeissenseeDepartment of Nuclear Medicine, University Hospital Bern, Inselspital, University of Bern, Rosenbühlgasse 25/27, CH-3010 , Bern, Switzerland.
Michelle AmonDepartment of Nuclear Medicine, University Hospital Bern, Inselspital, University of Bern, Rosenbühlgasse 25/27, CH-3010 , Bern, Switzerland.
Shayan AcikgözDepartment of Nuclear Medicine, University Hospital Bern, Inselspital, University of Bern, Rosenbühlgasse 25/27, CH-3010 , Bern, Switzerland.
Clemens MingelsDepartment of Nuclear Medicine, University Hospital Bern, Inselspital, University of Bern, Rosenbühlgasse 25/27, CH-3010 , Bern, Switzerland.
Justin FerdinandusDepartment I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany.
Foroud Aghapour ZangenehDepartment of Nuclear Medicine, University Hospital Bern, Inselspital, University of Bern, Rosenbühlgasse 25/27, CH-3010 , Bern, Switzerland.
Urban NovakDepartment of Medical Oncology, Inselspital, University Hospital Bern, University of Bern, Bern, Switzerland.
Thomas PabstDepartment of Medical Oncology, Inselspital, University Hospital Bern, University of Bern, Bern, Switzerland.
Axel RomingerDepartment of Nuclear Medicine, University Hospital Bern, Inselspital, University of Bern, Rosenbühlgasse 25/27, CH-3010 , Bern, Switzerland.
Kuangyu ShiDepartment of Nuclear Medicine, University Hospital Bern, Inselspital, University of Bern, Rosenbühlgasse 25/27, CH-3010 , Bern, Switzerland.
Hasan Sari *Department of Nuclear Medicine, University Hospital Bern, Inselspital, University of Bern, Rosenbühlgasse 25/27, CH-3010 , Bern, Switzerland.
Robert Seifert *Department of Nuclear Medicine, University Hospital Bern, Inselspital, University of Bern, Rosenbühlgasse 25/27, CH-3010 , Bern, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIt is unclear whether the use of contrast enhanced (CE) CT for attenuation correction (AC) of [

methodsLymphoma patients who underwent LAFOV-[

resultsSUV

conclusionThe use of CE-CT for AC of LAFOV-PET in UHS mode leads to higher SUV measurements. Also, lymphoma lesions show a consistent increase in uptake. The errors in the lesions seem higher than in conventional standard axial field-of-view PETs that use CE-CT for AC. Therefore, interpretation of borderline cases warrants attention to potential errors.

Indexed as

Attenuation correctionDeauvilleFDGFDG-PET/CTLAFOVLAFOV-PETLAFOV-PET/CTLymphomaPETPET/CT

Identifiers

PMID41973274
PMCPMC13184045

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.