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GuidelineSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026

MASCC clinical practice statement: Prevention and management of acute radiation dermatitis using topical corticosteroids.

Henry C Y Wong, Shing Fung Lee, Julie Ryan Wolf, Corina van den Hurk, Raymond J Chan, Maxwell Sauder, Jennifer Y Y Kwan, Michele Aquilano, Shirley S W Tse, Gustavo Nader Marta and 2 more

Abstract readPractice Guideline
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In one paragraph

Guideline in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

12 authors.

Henry C Y WongDepartment of Oncology, Princess Margaret Hospital, Kowloon West Cluster, Hospital Authority, 2-10 Princess Margaret Hospital Road, Lai Chi Kok, Kowloon, Hong Kong S.A.R, China. henrywong3011@gmail.com.
Shing Fung LeeDepartment of Radiation Oncology, National University Cancer Institute, National University Hospital, Singapore, Singapore.
Julie Ryan WolfDepartment of Radiation Oncology, University of Rochester, Rochester, NY, USA.
Corina van den HurkCatharina Hospital, Eindhoven and Santeon, Utrecht, Netherlands.
Raymond J ChanCaring Futures Institute, College of Nursing and Health Sciences, Flinders University, Adelaide, Australia.
Maxwell SauderDivision of Dermatology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Jennifer Y Y KwanRadiation Medicine Program, Princess Margaret Cancer Centre, Toronto, ON, Canada.
Michele AquilanoRadiation Oncology, Azienda Ospedaliero-Universitaria Careggi, University of Florence, Florence, Italy.
Shirley S W TseDepartment of Clinical Oncology, Queen Elizabeth Hospital, Kowloon Central Cluster, Hospital Authority, Kowloon, Hong Kong S.A.R, China.
Gustavo Nader MartaDepartment of Radiation Oncology, Hospital Sírio-Libanês, São Paulo, Brazil.
Edward ChowOdette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
Pierluigi BonomoRadiation Oncology, Azienda Ospedaliero-Universitaria Careggi, University of Florence, Florence, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeA MASCC Clinical Practice Statement (CPS) serves as a brief, practical, clinician-oriented tool that highlights essential information for managing complications from anti-cancer treatments in cancer patients. This CPS provides guidance on the use of topical corticosteroids (TC) in the prevention and management of acute radiation dermatitis (ARD).

methodsThis CPS was developed based on a critical evaluation of the literature identified through a search in MEDLINE till November 23, 2025, followed by a structured discussion of a group of experts of the MASCC Oncodermatology Study Group. The information is summarised in concise bullet points to create a brief manual on optimal standard care practices.

resultsRecommendations were provided regarding patient selection criteria for TC in the prevention and management of ARD. Guidance was also presented on the optimal choice of TC, its timing, schedule, application details, and monitoring of clinical effects to achieve the best outcomes based on existing literature.

conclusionTCs are recommended for the prevention of ARD in selected patients with head and neck and breast cancers at a high risk of ARD. TC is also a treatment option for the management of patients with early ARD without evidence of moist desquamation. Medium potency TCs, such as mometasone furoate 0.1% cream, are preferred. Healthcare professionals should monitor patients' skin weekly during radiation and guide steroid use, discontinuing it if moist desquamation or other complications arise.

Indexed as

Adrenal Cortex HormonesRadiodermatitisAcute DiseaseAdministration, TopicalBreast NeoplasmsFemaleHead and Neck NeoplasmsHumansPatient SelectionAdrenal Cortex HormonesOncodermatologyRadiation dermatitisTopical corticosteroids

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.