Evidence map›Paper›PMID 41973205›Full record

ReviewEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Surgical management of ventral epidural cerebrospinal fluid leak: a scoping review and illustrative case.

Aaradhya Pant, Kelly Yoo, Ummey Hani, Ethan Schonfeld, Lindsay Park, Nicholas Telischak, Anand Veeravagu

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In one paragraph

Review in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aaradhya PantDepartment of Neurosurgery, Stanford Medicine, Stanford, USA. rdpant@stanford.edu.
Kelly YooDepartment of Neurosurgery, Stanford Medicine, Stanford, USA.
Ummey HaniDepartment of Neurosurgery, Stanford Medicine, Stanford, USA.
Ethan SchonfeldDepartment of Neurosurgery, Stanford Medicine, Stanford, USA.
Lindsay ParkDepartment of Neurosurgery, Stanford Medicine, Stanford, USA.
Nicholas TelischakDepartment of Radiology, Stanford Medicine, Stanford, USA.
Anand VeeravaguDepartment of Neurosurgery, Stanford Medicine, Stanford, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSpontaneous intracranial hypotension (SIH) is a neurological disorder caused by cerebrospinal fluid (CSF) leaks, most often spinal in origin, and is characterized by orthostatic headache, nausea, and cognitive impairment that can markedly reduce quality of life. Epidural blood patching (EBP) is first-line therapy, but spinal leaks due to ventral dural tears are less likely to respond and often require surgical repair. This scoping review synthesizes current evidence on surgical management of ventral spinal CSF leaks from dural tears and presents an illustrative case of osteophyte-related SIH.

methodsA comprehensive database search in PubMed, Web of Science, SCOPUS, and EMBASE was conducted. Studies reporting operative strategies for SIH due to ventral dural tears were included. Data were extracted on diagnostic methods, surgical techniques, and outcomes.

resultsSeventeen studies reporting operative strategies for ventral dural tear-associated spinal CSF leak leading to SIH were included. Posterior transdural techniques were most frequently described, with recent literature increasingly reporting minimally invasive approaches from a select number of specialized centers. Minimally invasive approaches have been reported with favorable outcomes and acceptable complication rates in recent series. The illustrative case demonstrates successful surgical repair without prior EBP trials in a patient with a severe, high-flow ventral leak, resulting in complete symptom resolution.

conclusionSurgical management of ventral dural tear-related CSF leaks has evolved, with minimally invasive techniques demonstrating favorable outcomes in selected series. However, interpretation of comparative outcomes to open approaches is limited by heterogeneity of outcomes, era effects in surgeon experience and techniques, and potential overlap among reporting centers. Accurate leak localization using advanced imaging and a tailored, algorithmic management strategy remain essential. Prospective comparative studies evaluating long-term outcomes and cost-effectiveness are needed to inform best practice.

Indexed as

Cerebrospinal Fluid LeakDural TearMinimally Invasive Spine SurgeryOsteophyteSpontaneous Intracranial Hypotension

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.