Evidence map›Paper›PMID 41973191›Full record

ArticleClinical and experimental gastroenterology2026

Omalizumab-Induced Remission and Steroid Withdrawal in Refractory Eosinophilic Gastroenteritis with Severe Hypereosinophilia: A Case Report.

Zhirong Du, Weixun Zhou, Ji Li, Li Ma, Qingli Zhu, Yuxiang Zhi

Abstract readCase Reports
In one paragraph

Article in Clinical and experimental gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhirong DuDepartment of Allergy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing Key Laboratory of Precision Medicine for Diagnosis and Treatment of Allergic Disease, National Clinical Research Center for Dermatologic and Immunologic Diseases, Beijing, 100730, People's Republic of China.
Weixun ZhouDepartment of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, 100730, People's Republic of China.ORCID 0000-0002-7459-7343
Ji LiDepartment of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, 100730, People's Republic of China.
Li MaDepartment of Ultrasound, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, 100730, People's Republic of China.
Qingli ZhuDepartment of Ultrasound, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, 100730, People's Republic of China.
Yuxiang ZhiDepartment of Allergy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing Key Laboratory of Precision Medicine for Diagnosis and Treatment of Allergic Disease, National Clinical Research Center for Dermatologic and Immunologic Diseases, Beijing, 100730, People's Republic of China.ORCID 0000-0001-7539-6650

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eosinophilic gastroenteritis (EGE) is a rare, immune-mediated disorder characterized by pathological eosinophilic infiltration of the gastrointestinal tract. Corticosteroids are the primary treatment for EGE, but managing patients who are corticosteroid-dependent can be challenging. This report describes a 33-year-old female patient with EGE and severe hypereosinophilia, who was corticosteroid-dependent and had been on long-term oral corticosteroids for 5 years with an increasing maintenance dose. The patient achieved effective treatment with omalizumab without adverse reactions. This case provides evidence for the efficacy and safety of omalizumab in patients with corticosteroid-dependent eosinophilic gastroenteritis and severe hypereosinophilia.

Indexed as

eosinophilic gastroenteritishypereosinophiliaomalizumab

Identifiers

PMID41973191
PMCPMC12791163

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.