Evidence map›Paper›PMID 41973056›Full record

ArticleCentral European journal of public health2026

Factors influencing attitudes toward vaccination in general and against COVID-19 among family medicine patients with and without chronic disease in Croatia.

Vedrana Tudor Špalj, Branislava Popović, Nives Radošević Quadranti, Gordana Mičetić Balog, Zoran Adžić

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Article in Central European journal of public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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5 authors.

Vedrana Tudor ŠpaljDepartment of Family Medicine, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Branislava PopovićDepartment of Family Medicine, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Nives Radošević QuadrantiDepartment of Family Medicine, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Gordana Mičetić BalogDepartment of Family Medicine, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Zoran AdžićDepartment of Family Medicine, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of the study was to analyse the attitudes and decisions regarding vaccination in general and against COVID-19 among general practitioner (GP) patients in Croatia, and to identify influencing factors, with particular attention to chronic conditions and anxiety.

methodsA total of 184 patients (stratified by sex and presence of chronic disease) from a GP's offices, aged 18-87 years (average 50.3 ± 1.3 years, 49.5% women) were included. Data were collected using a questionnaire.

resultsAttitudes toward vaccination in general did not differ between patients with and without chronic diseases and were not influenced by anxiety. Chronically ill patients were more likely than those without chronic disease to believe in the efficacy of the COVID-19 vaccine and to express fear of contracting SARS-CoV-2 (p ≤ 0.003). Anxiety was associated with fear of infection (p < 0.001), but not with confidence in vaccine safety or efficacy. After controlling for sex, age, education, chronic illness, anxiety, and knowing someone infected and hospitalized with SARS-CoV-2, factors associated with the decision to be vaccinated against COVID-19 were absence of prior infection (OR = 3.9, 95% CI: 1.6-9.5, p = 0.003), history of influenza vaccination (OR = 3.8, 95% CI: 1.4-10.4, p = 0.009), and knowing someone who had died from COVID-19 (OR = 3.2, 95% CI: 1.1-9.7, p = 0.037).

conclusionThe decision to vaccinate against COVID-19 was associated with absence of prior infection, knowing someone who died from the disease, and prior influenza vaccination, but not with chronic illness, anxiety, or socio-demographic factors.

Indexed as

COVID-19COVID-19 VaccinesFamily PracticeHealth Knowledge, Attitudes, PracticeVaccinationAdolescentAdultAgedAged, 80 and overAnxietyChronic DiseaseCroatiaFemaleHumansMaleMiddle AgedCOVID-19 Vaccinesanxietychronic diseasesCOVID diseasefamily medicinevaccination

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.