Evidence map›Paper›PMID 41972873›Full record

ArticleFuture science OA2026

Ultrasound-guided injection strategies for lateral epicondylitis: a multicenter randomized comparison of corticosteroid, platelet-rich plasma, and ozone.

Seyed Ahmad Raeissadat, Davood Khavari Ardestani, Seyyede Elahe Mousavikhah, Masume Bayat, Marzieh Babaee, Mahfam PourAzin

Abstract read
In one paragraph

Article in Future science OA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Seyed Ahmad RaeissadatClinical research development center of Shahid Modarres hospital, Physical medicine and rehabilitation department, School of medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Davood Khavari ArdestaniClinical research development center of Shahid Modarres hospital, Physical medicine and rehabilitation department, School of medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Seyyede Elahe MousavikhahClinical research development center of Shahid Modarres hospital, Physical medicine and rehabilitation department, School of medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Masume BayatClinical research development center of Shahid Modarres hospital, Physical medicine and rehabilitation department, School of medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Marzieh BabaeePhysical Medicine and Rehabilitation Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mahfam PourAzinClinical research development center of Shahid Modarres hospital, Physical medicine and rehabilitation department, School of medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the effectiveness of ultrasound-guided injections of corticosteroid, platelet-rich plasma (PRP), and ozone for treating chronic lateral epicondylitis.

methodsThis multi-center, three-arm, assessor-blinded, randomized controlled trial enrolled 90 patients with chronic lateral epicondylitis. Participants were randomized in a 1:1:1 ratio to receive a single ultrasound-guided injection of either methylprednisolone, low-leukocyte PRP, or medical ozone. The primary outcomes were pain on the visual analog scale (VAS), function via the Mayo Elbow Performance Index (MEPI), and the pressure pain threshold (PPT), assessed at baseline, 8 weeks, and 6 months.

resultsEighty of the 90 randomized patients completed the study. All three treatment groups demonstrated statistically significant improvements from baseline across all primary outcome measures at both the 8-week and 6-month follow-ups (

conclusionUltrasound-guided injections of corticosteroid, low-leukocyte PRP, and ozone are all effective treatments for improving pain and function in patients with chronic lateral epicondylitis at 6 months. As no single agent proved statistically superior, the choice of therapy should be guided by a process of shared decision-making that considers factors such as patient preference, cost, and desired timeline for relief.

Indexed as

blood plateletsinjectionsintra-articularozone/therapeutic useregenerative medicineTennis elbowtreatment outcome

Identifiers

PMID41972873
PMCPMC13078189

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.