ArticleCancer medicine2026
Population-Based Associations of Body Mass Index and Treatments Received for Breast Cancer in a Rural, Midwestern State.
Article in Cancer medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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7 authors.
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Abstract
purposeBreast cancer patients with higher body mass index (BMI) experience worsened outcomes, though a knowledge gap remains regarding whether treatment differs by BMI. This study examined how BMI was associated with breast cancer treatment among Iowans.
methodsIowa Cancer Registry data were linked with state driver's license data to calculate BMI. Among those with stage I-III cancers, we assessed differences in breast cancer surgery (BCS), reconstruction, chemotherapy, hormone therapy, and radiation therapy between BMI categories using logistic regression models. We restricted analyses of reconstruction to individuals who received surgery, and hormone therapy to hormone receptor-positive (HR+) patients. We used multinomial models to assess the type of BCS received.
resultsNearly all of the 18,115 included patients received surgery (97%), 63% received chemotherapy, 79% of HR+ patients received hormone therapy, and 63% received radiation therapy. Patients with higher BMI had decreased odds for reconstruction (BMI 25.0-29.9 kg/m DISCUSSION: These findings suggest breast cancer treatment differences exist for patients with higher BMI. Future research is warranted to understand mechanisms behind differences, both to ensure breast cancer patients with higher BMIs receive adequate and appropriate cancer care and to understand whether treatment differences contribute to observed survival differences.
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