Human Nasal Cells in Nanofibrillar Cellulose Hydrogel: Viability, Function, and Implications for Bone Tissue Regeneration.

Marijana Sekulic, Alina Korah, Simona Negoias, Daniel Bodmer, Vesna Petkovic

Abstract read

In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marijana SekulicDepartment of Biomedicine, University of Basel, University Hospital Basel, 4031 Basel, Switzerland.ORCID 0000-0002-3761-7253

Alina KorahFaculty of Medicine, University of Basel, 4056 Basel, Switzerland.

Simona NegoiasOtorhinolaringology Department, University Hospital Basel, 4031 Basel, Switzerland.

Daniel BodmerOtorhinolaringology Department, University Hospital Basel, 4031 Basel, Switzerland.

Vesna PetkovicDepartment of Biomedicine, University of Basel, University Hospital Basel, 4031 Basel, Switzerland.

Funding

Freiwillige Akademische Gesellschaft (FAG). 0000

6 · The paper itself

Abstract

Endoscopic sinus surgery (ESS) is commonly performed to treat chronic rhinosinusitis and selected sinonasal tumors, yet postoperative complications such as neo-osteogenesis and restenosis remain frequent, largely due to impaired mucosal regeneration after extensive epithelial and bony tissue loss. Successful nasal epithelial repair requires a microenvironment that preserves cell viability, phenotype, and barrier integrity. Conventional culture substrates often lack physiological relevance or rely on animal-derived components, limiting translational applicability. In this study, we evaluated nanofibrillar cellulose (NFC) hydrogel (GrowDex

Indexed as

Bone RegenerationCelluloseHydrogelsNanofibersNasal MucosaCells, CulturedCell SurvivalEpithelial CellsHumansTissue ScaffoldsCelluloseHydrogelsbone tissue regenerationnanofibrillar cellulose hydrogelnasal epithelial cellspermeabilityTEER

Identifiers

PMID41972729

DOI10.3390/cells15070641

PMCPMC13073541

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.