Evidence map›Paper›PMID 41972723›Full record

ReviewCells2026

Tubular Aggregate Myopathies: Genetic Heterogeneity and Diverse Clinical Features Converging on Calcium Dysregulation.

Matteo Serano, Federica Fiore, Vincenzo Sorrentino, Daniela Rossi

Abstract readReview
In one paragraph

Review in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Matteo SeranoDepartment of Molecular and Developmental Medicine, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-4151-2980
Federica FioreDepartment of Molecular and Developmental Medicine, University of Siena, 53100 Siena, Italy.
Vincenzo SorrentinoDepartment of Molecular and Developmental Medicine, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-8573-8631
Daniela RossiDepartment of Molecular and Developmental Medicine, University of Siena, 53100 Siena, Italy.ORCID 0000-0003-0463-7327

Funding

AFM-Telethon 24835European Union, Center for Gene Therapy and Drugs Based on RNA Technology, (NRRP), M4C2 Inv, 1.4 CUP B63C22000610006 - Spoke 1European Union, Tuscan Health Ecosystem,(NRRP) M4C2 1.5 CUP B63C22000680007 - Spoke 7Italian Telethon GGP19231
6 · The paper itself

Abstract

Tubular aggregate myopathy (TAM) is a rare inherited muscle disorder characterized by the abnormal accumulation of tubular aggregates (TAs) within skeletal muscle fibers. These aggregates, composed of compacted sarcoplasmic reticulum (SR) tubules, are strongly linked to disturbances in calcium (Ca

Indexed as

CalciumGenetic HeterogeneityMyopathies, Structural, CongenitalAnimalsHumansMutationCalciumcalsequestrin1 (CASQ1)myopathyskeletal muscle contractiontubular aggregate myopathy (TAM)

Identifiers

PMID41972723
PMCPMC13072200

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.