Hybrid CNN-GCN framework for brain tumor MRI classification: A graph-based approach to smart healthcare diagnostics.

backgroundAccurate classification of brain tumors is a major challenge in neuro-oncology, as the heterogeneity of tumor morphology and the overlap of radiological features limit the effectiveness of conventional diagnostic approaches. Early and reliable tumor characterization is essential for treatment planning, prognosis, and improved patient outcomes. Recent advances in artificial intelligence (AI) have enabled the development of deep learning frameworks that can augment radiological interpretation and support clinical decision-making.

objectiveThis study proposes and validates a hybrid computational framework that integrates convolutional neural networks (CNNs) with graph convolutional networks (GCNs) for automated classification of brain tumors from magnetic resonance imaging (MRI).

methodsA publicly available Kaggle-based MRI dataset was utilized, consisting of four categories: glioma, meningioma, pituitary tumor, and no-tumor. The proposed pipeline incorporated systematic preprocessing, transfer learning via the InceptionV3 architecture for hierarchical feature extraction, graph construction to model inter-feature relationships, and GCN-based relational learning for final classification. Hyperparameter optimization was performed using Particle Swarm Optimization (PSO) to improve generalizability.

resultsThe experimental evaluation achieved an overall classification accuracy of 92.91%. Class-specific performance analysis demonstrated particularly high diagnostic accuracy in the no-tumor group (F1-score: 0.9963) and pituitary tumor group (F1-score: 0.9599). The incorporation of PSO tuning further improved the validation accuracy to 94.23%. The hybrid CNN-GCN framework exhibited robustness against imaging artifacts and irregular tumor boundaries, conditions that commonly challenge conventional classification techniques.

conclusionThe integration of CNN-based hierarchical feature extraction with GCN-based relational reasoning provides a significant advancement in automated brain tumor classification. This reproducible and intelligent diagnostic pipeline demonstrates strong potential for clinical translation by enhancing diagnostic precision, reducing radiologist workload, and facilitating timely therapeutic interventions. The findings support the integration of graph-based deep learning systems into smart healthcare ecosystems, where AI-assisted diagnostic tools can contribute to improved outcomes in neuro-oncology.