Evidence map›Paper›PMID 41972305›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Multidimensional and Multifunctional Laser-Induced Graphene (LIG) for Point-of-Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine.

Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak

Abstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Li ZhangDepartment of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong, China.
Yurou YuanDepartment of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong, China.
Xiaohong DingDepartment of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong, China.
Wing Cheung MakDepartment of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong, China.ORCID https://orcid.org/0000-0003-3274-6029

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multidimensional laser-induced graphene (LIG) has emerged as an attractive signal transduction and bioactive material, functioning both as high-performance biosensors and multifunctional biomedical platforms. Its unique porous, graphene-like morphology offers multiple advantageous features, including high conductivity, tunable surface energy, high active surface area, catalytic activity, biocompatibility, and mechanical flexibility, along with facile fabrication through a chemical-free, mask-free, and programmable laser writing process. Yet, the exploration of its dimensional versatility, spanning from 0D to 3D architectures, facilitates multifunctional biomedical applications for personalized healthcare and regenerative medicine remain challenging. This review summarizes recent advances in LIG-based platforms for personalized healthcare and regenerative medicine, beginning with LIG-based transducers for various biosensing modalities, including physiochemical, point-of-care, and wearable biosensing. We further examine LIG-based platforms serving as bioactive interfaces for advanced multifunctional biomedical applications, including anti-microbial strategies, smart drug delivery, closed-loop theranostic platforms, lab-on-a-chip systems, and regenerative medicine applications such as tissue engineering and cell scaffolding. Emerging directions, including LIG-optics, LIG-based organ-on-a-chip platforms, smart 4D LIG material, and AI-powered LIG systems, are also discussed. By bridging LIG's multidimensional architectures and multifunctional capabilities, this review highlights the potential of LIG materials to advance the development of future personalized healthcare and regenerative medical systems.

Indexed as

bioactive interfacesbiosensorslaser‐induced graphene (LIG)personalized healthcareregenerative medicinetheranostics

Identifiers

PMID41972305
PMCPMC13334942

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.