Evidence map›Paper›PMID 41972090›Full record

ArticleQuantitative imaging in medicine and surgery2026

Objective value of the apparent diffusion coefficient (ADC) map from ultrahigh b-value diffusion-weighted imaging (DWI) in 3T MRI as a non-invasive predictor for Gleason score in prostate cancer.

Kun Zhang, Zhengming Chen, Chen Zhang, Meifeng Wang, Yonggui Fu, Yun Zhang, Yingying Hu, Yanguang Shen, Huiyi Ye

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Article in Quantitative imaging in medicine and surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

9 authors.

Kun Zhang *Department of Radiology, The Sixth Medical Center of Chinese PLA General Hospital, Beijing, China.
Zhengming Chen *Department of Radiology, The Sixth Medical Center of Chinese PLA General Hospital, Beijing, China.
Chen Zhang *Department of Radiology, The Sixth Medical Center of Chinese PLA General Hospital, Beijing, China.
Meifeng WangDepartment of Radiology, The Sixth Medical Center of Chinese PLA General Hospital, Beijing, China.
Yonggui FuDepartment of Radiology, The Sixth Medical Center of Chinese PLA General Hospital, Beijing, China.
Yun ZhangDepartment of Radiology, Peking University International Hospital, Beijing, China.
Yingying HuDepartment of Radiology, Peking University International Hospital, Beijing, China.
Yanguang Shen *Department of Radiology, Beijing University of Chinese Medicine Third Affiliated Hospital, Beijing, China.
Huiyi Ye *Department of Radiology, Chinese PLA General Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Accurate risk stratification of prostate cancer (PCa) is crucial for clinical management. Although diffusion-weighted imaging (DWI) is widely used in PCa evaluation, the value of high and ultrahigh b-values remains under investigation. This study aimed to explore the predictive value of ultrahigh b-value DWI for the Gleason score of PCa patients. Methods: This study gathered a total of 78 patients and acquired T2-weighted imaging (T2WI), conventional DWI (0, 1,000 s/mm Results: A total of 154 biopsy-confirmed lesions (102 cancerous lesions and 52 noncancer lesions) were analyzed. Ultrahigh b-value DWI (b=2,000 and 3,000 s/mm Conclusions: Ultrahigh b-value DWI with quantitative ADC measurements can be an effective indicator for evaluating the differentiation of PCa. It has important value for the clinical prediction of Gleason scores and prognosis assessment.

Indexed as

apparent diffusion coefficient (ADC)Gleason scoremagnetic resonance imaging (MRI)Prostatic neoplasmsultrahigh b-value diffusion-weighted imaging (ultrahigh b-value DWI)

Identifiers

PMID41972090
PMCPMC13066855

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