ArticleQuantitative imaging in medicine and surgery2026
Left ventricular parameters and mass indexing methods in cardiac magnetic resonance imaging in prediction of major adverse cardiovascular events and mortality.
Article in Quantitative imaging in medicine and surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Increased left ventricular mass (LVM) is a predictor of adverse outcomes. We investigated which cardiac magnetic resonance (CMR) imaging parameters and LVM indexing methods are associated with major adverse cardiovascular events (MACEs) and mortality. Methods: In this exploratory analysis, we included patients with known cardiovascular diseases who underwent CMR. Left ventricular hypertrophy (LVH) was defined as LVM >148 g for men or >96 g for women. Moreover, various LVM indexing methods were studied including indexing to body surface area (BSA) with cut-off values determined by the Multi-Ethnic Study of Atherosclerosis (MESA). The data on the MACE and mortality occurrence in the 6-year follow-up were collected. Results: The study group included 84 patients with a median age of 45.0 (32.0-60.0) years (26% were female). The majority of patients had established cardiovascular disease (77%), and 51% had preserved left ventricular ejection fraction (LVEF). MACE occurred in 14 (16.7%) patients, while 5 patients (6.0%) died. Heart failure, increased LVM/BSA (MESA) and low left ventricular stroke volume (LVSV) were associated with MACE [79% Conclusions: Selected CMR-derived parameters, particularly LVSV and LVM indexed using MESA-derived cut-off values may be associated with adverse clinical outcomes. Further research on predictive meaning of CMR-derived parameters, utilizing larger, adequately powered studies is needed.
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