ArticleQuantitative imaging in medicine and surgery2026
Phenotyping preserved ratio impaired spirometry (PRISm) using quantitative high-resolution computed tomography imaging features.
Article in Quantitative imaging in medicine and surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Preserved ratio impaired spirometry (PRISm) is characterized by decreased forced expiratory volume in 1 second (FEV Methods: This retrospective study enrolled 102 cases with PRISm from December 2020 to July 2023. All patients underwent inspiration computed tomography (CT) scanning and pulmonary function testing (PFT) within 3 months. The parenchyma and airway parameters were measured by automatic segmentation software (IntelliSpace Portal) with quantitative and semi-quantitative analysis, respectively. One-way analysis of variance (ANOVA) was used to compare the differences in demographic data, PFT characteristics, and CT parameters among groups. Pearson's or Spearman's correlation analysis was used to investigate the correlation between quantitative CT parameters and lung function indices. Results: The parenchyma and airway parameters, including total lung capacity on CT (TLC Conclusions: There were differences in quantitative parenchyma and airway parameters and parts of PFT results in different morphological phenotypes based on HRCT, which may contribute to the stratification of PRISm patients by a novel radiological method.
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