ArticleActa stomatologica Croatica2026
Adjunctive Povidone-Iodine Improves Bleeding Outcomes in Step 2 of Periodontal Therapy: A Retrospective Cohort Study.
Article in Acta stomatologica Croatica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: This retrospective cohort study evaluated the effects of adjunctive povidone-iodine (PVP-I), full-mouth disinfection (FMD), and conventional full-mouth scaling (FMS) following Step 2 of periodontal therapy on clinical outcomes. Methods: Patient records from the Department of Conservative Dentistry, University Hospital Tubingen (2004-2016), with complete periodontal data before (T0) and after Step 2 of periodontal therapy (T1), were analyzed. The influence of treatment modality, baseline bleeding on probing (BOP%), proportion of sites with probing pocket depth (PPD) ≥ 5 mm, age, smoking, diabetes, and re-evaluation interval on changes in BOP and PPD, as well as on the clinical endpoints Results: A total of 227 patients were included (52% female; mean ± SD age: 56.5 ± 11.2 years): 96 FMS, 93 FMD, and 38 PVP-I. Adjunctive PVP-I led to a significantly greater reduction in BOP compared with both FMD and FMS and substantially increased the likelihood of achieving Conclusion: Adjunctive PVP-I use was significantly associated with improved bleeding-related outcomes after Step 2 of periodontal therapy, whereas no additional benefit was observed for deep-pocket reduction. PVP-I may therefore enhance the resolution of gingival inflammation but does not substantially affect pocket closure beyond conventional mechanical therapy.
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