ArticleAME case reports2026
Cardiorespiratory fitness, muscular strength, balance and tumor biomarker dynamics following a multimodal exercise-nutrition intervention in a multimorbid elderly colorectal cancer survivor with liver metastasis: a case report.
Article in AME case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Older survivors of metastatic colorectal cancer frequently present with multimorbidity, functional impairment, and limited evidence-based guidance for non-pharmacological treatment. This case report describes a complex geriatric colorectal cancer survivor with a history of liver metastasis and significant comorbidity who underwent a supervised multimodal exercise-nutrition intervention. Case Description: A 78-year-old colorectal cancer survivor with previous hepatic metastasis completed an 8-week supervised concurrent exercise and nutritional intervention. The intervention program primarily combined aerobic, resistance, and balance training with a Mediterranean- and Nordic-style diet emphasizing anti-inflammatory and antioxidant foods. Outcomes included anthropometry, cardiorespiratory performance via a 6-minute walk test with gas analysis, lower-limb strength (sit-to-stand test), postural balance on a force platform, and tumor biomarkers [carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA 19-9)]. Functional outcomes demonstrated marked improvements: walking distance during the six-minute walk test increased by 52%, oxygen uptake during the 6MWT by 50%, and lower-limb strength by 33%. Balance assessments revealed significant reductions in sway area (-35.6% eyes open; -51.8% eyes closed), indicating improved postural stability. These physiological adaptations were accompanied by modest reductions in body weight (-4.3%) and resting heart rate (-10.8%). Following the intervention, serum CEA and CA 19-9 levels decreased by 48.8% and 31.2%, respectively, with CEA reaching the normal range. Conclusions: This case illustrates the feasibility and clinical relevance of a supervised, multimodal exercise-nutrition intervention in a multimorbid, elderly survivor of metastatic colorectal cancer. The pronounced improvements in cardiorespiratory fitness, muscular strength, and balance represent the most robust findings, while observed tumor biomarker dynamics should be interpreted cautiously. Although causality cannot be inferred, these observations highlight the potential role of personalized lifestyle-based rehabilitation strategies within survivorship care and support further investigation in longitudinal and controlled studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.