Evidence map›Paper›PMID 41971795›Full record

ArticleFundamental research2026

L-palmitoylcarnitine supplementation improves oocyte quality and embryo development derived from obese mice.

Juan Ge, Junjie Guo, Xiang Zhang, Weizheng Yang, Longsen Han, Hongzheng Sun, Hui Wang, Qiang Wang

Abstract read
In one paragraph

Article in Fundamental research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Juan GeState Key Laboratory of Reproductive Medicine and Offspring Health, Changzhou Maternity and Child Health Care Hospital, Changzhou Medical Center, Nanjing Medical University, Nanjing 211166, China.
Junjie GuoState Key Laboratory of Reproductive Medicine and Offspring Health, Changzhou Maternity and Child Health Care Hospital, Changzhou Medical Center, Nanjing Medical University, Nanjing 211166, China.
Xiang ZhangState Key Laboratory of Reproductive Medicine and Offspring Health, Changzhou Maternity and Child Health Care Hospital, Changzhou Medical Center, Nanjing Medical University, Nanjing 211166, China.
Weizheng YangState Key Laboratory of Reproductive Medicine and Offspring Health, Changzhou Maternity and Child Health Care Hospital, Changzhou Medical Center, Nanjing Medical University, Nanjing 211166, China.
Longsen HanState Key Laboratory of Reproductive Medicine and Offspring Health, Changzhou Maternity and Child Health Care Hospital, Changzhou Medical Center, Nanjing Medical University, Nanjing 211166, China.
Hongzheng SunState Key Laboratory of Reproductive Medicine and Offspring Health, Changzhou Maternity and Child Health Care Hospital, Changzhou Medical Center, Nanjing Medical University, Nanjing 211166, China.
Hui WangDepartment of Histology and Embryology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing 211166, China.
Qiang WangState Key Laboratory of Reproductive Medicine and Offspring Health, Changzhou Maternity and Child Health Care Hospital, Changzhou Medical Center, Nanjing Medical University, Nanjing 211166, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Changes in fatty acid composition caused by diet or exposure to diets that promote obesity can impact the quality of eggs and embryos, as well as the health of the resulting offspring. Palmitoylcarnitine, as an important intermediate for fatty acid transport across the inner mitochondrial membrane, undergoes a substantial increase during oocyte maturation. However, its impact on oocyte/embryo development remains unknown. In the present study, by establishing a high-fat diet (HFD)-induced model of obesity, we systematically evaluated the effects of palmitoylcarnitine supplementation on oocyte competence and embryo quality derived from obese mice. We found that palmitoylcarnitine supplement during

Indexed as

EmbryoL-palmitoylcarnitineObesityOocyteReproduction

Identifiers

PMID41971795
PMCPMC13069659

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.