ArticleChinese herbal medicines2026
Optimization of imperatorin extraction from Qianliexin Capsules using deep eutectic solvent.
Article in Chinese herbal medicines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: As a novel drug, Qianliexin Capsules (QLX) have promising therapeutic potential in the treatment of prostate diseases. The drug has a demonstrated efficacy on improving urinary disorders caused by diseases such as enlarged prostate, prostatitis and prostate cancer. The primary bioactive constituent in QLX is imperatorin (IMP). The objective of this study was to establish an environmentally friendly extraction process for the efficient extraction of IMP from QLX. Methods: Nine deep eutectic solvents (DESs) were systematically designed for efficient extraction of IMP from QLX. The extraction efficiency of IMP was quantitatively determined via HPLC. A sequential optimization strategy combining single-factor experiments and response surface methodology (RSM) was employed to identify the optimal extraction conditions. The Results: Under optimal conditions, the extraction yield of IMP reached 534.19 mg/g, which proves the high efficiency of DES. The Conclusion: In this study, an environmentally friendly and efficient extraction process was established and successfully applied to the extraction of IMP from QLX. The experimental results show that this method shows remarkable application potential and provides a new research idea for the extraction of QLX active ingredients.
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