ArticleISME communications2026
The adaptation chip: repurposing the principles of the ichip for guiding in situ experimental evolution.
Article in ISME communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Soil microbial ecosystems are complex and difficult to replicate in laboratory settings. It is often unclear which pressures most strongly shape microbial survival and evolution in situ, and new methods are needed to intersect the manipulative power of the lab with the reality of field environments. One recent innovation was the "isolation chip," in which many new microbial isolates could be cultured on agar within a buried diffusion chamber while exposed to environmental inputs through fine-pored membranes. Here, we created a modified version of this device containing biologically-cleared soil instead of agar, to trial an in situ reverse ecology experimental evolution approach. Using these "adaptation chips (aChips)" we exposed populations of two different soil-dwelling bacteria (
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