Evidence map›Paper›PMID 41971374›Full record

ReviewFrontiers in nutrition2026

The role and application prospects of plant-derived bioactive peptides in exercise fatigue recovery.

Zhan Gao, Xiupeng Yin, Qinglei Cao

Abstract readReview
In one paragraph

Review in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zhan GaoBasketball Teaching and Research Office, Capital University of Physical Education and Sports, Beijing, China.
Xiupeng YinSchool of Ecology and Environment, Zhengzhou University, Zhengzhou, China.
Qinglei CaoDepartment of Physical Education, University of Science and Technology Beijing, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exercise-induced fatigue is a regular physiological event that impairs sports performance and prolongs recovery time. While conventional recovery methods exist, there is a pressing need for natural, effective, and sustainable alternatives. This review aims to comprehensively review the emerging role of plant-derived bioactive peptides (PBPs) in sports nutrition, highlighting their innovative potential compared to traditional supplements. We demonstrate that PBPs alleviate fatigue through multi-targeted remarkable mechanisms: scavenging reactive oxygen species (ROS) to mitigate oxidative stress, downregulating pro-inflammatory cytokines to protect muscle tissue, and activating specific metabolic pathways (e.g., AMPK) to accelerate glycogen resynthesis and optimize energy utilization. Consequently, the application of PBPs offers a compelling solution to delay fatigue and accelerate physical recovery. However, the field faces significant new challenges, including the lack of standardized dosages, unmapped structure-activity relationships, and a scarcity of human clinical trials. By addressing these unexplored aspects, this study provides a critical theoretical foundation and future directions for developing PBPs as next-generation functional ingredients in personalized sports nutrition.

Indexed as

anti-inflammatoryantioxidantenergy metabolismexercise fatigueplant-derived bioactive peptidessports nutrition

Identifiers

PMID41971374
PMCPMC13066138

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.