Evidence map›Paper›PMID 41971345›Full record

ArticleFrontiers in microbiology2026

The temporal sequence of influenza H1N1 and

Junchi Ma, Yanyan Li, Weihua Jin, Xueqian Xie, Aiyi Li, Yanan Wu, Fengmei Yang, Suqin Duan, Mingxue Li, Haiting Long and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Junchi Ma *Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, China.
Yanyan Li *Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, China.
Weihua JinInstitute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, China.
Xueqian XieInstitute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, China.
Aiyi LiInstitute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, China.
Yanan WuInstitute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, China.
Fengmei YangInstitute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, China.
Suqin DuanInstitute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, China.
Mingxue LiInstitute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, China.
Haiting LongInstitute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, China.
Zhanlong HeInstitute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, China.
Yuan ZhaoInstitute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Influenza H1N1 virus is one of the most prevalent subtypes among influenza viruses, and co-infection with Methods: In this study, we established a model of influenza H1N1 and Results: The results demonstrated that hamsters first infected with H1N1 followed by Mp (F-M group) exhibited significantly more severe histopathological lesions (assessed by HE staining), higher pathogen loads, and dysregulated cytokine responses compared to other infection groups. Conclusion: Our findings highlight the critical role of infection order in determining the severity of H1N1-Mp co-infection, providing novel insights into the temporal dynamics and pathogenic mechanisms of respiratory co-infections.

Indexed as

co-infectioninfluenza H1N1 virusMycoplasma pneumoniaerespiratory infectious diseaseSyrian hamstertemporal sequence

Identifiers

PMID41971345
PMCPMC13066289

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.