Evidence map›Paper›PMID 41971176›Full record

ArticlePerspectives on medical education2026

Patient Safety in Anticoagulation: Implementing Safety-II and FRAM in the Medical Curriculum.

Lauren S Baidjoe, Liselotte M van Dijk, Mirjam Simoons, An Tran, Marieke J H A Kruip, Jorie Versmissen, Floor van Rosse

Abstract read
In one paragraph

Article in Perspectives on medical education, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lauren S BaidjoeDepartment of Hospital Pharmacy, Erasmus MC, University Medical Center Rotterdam, The Netherlands.ORCID 0009-0002-6264-025X
Liselotte M van DijkProgram Healthcare Transformation, St. Antonius Hospital, Nieuwegein, The Netherlands.ORCID 0000-0002-5747-7163
Mirjam SimoonsDepartment of Hospital Pharmacy, Erasmus MC, University Medical Center Rotterdam, The Netherlands.ORCID 0000-0001-8674-4999
An TranProgram Healthcare Transformation, St. Antonius Hospital, Nieuwegein, The Netherlands.
Marieke J H A KruipDepartment of Hematology and Department of Quality and Patient Care, Erasmus MC, University Medical Center Rotterdam, The Netherlands.ORCID 0000-0002-0265-4871
Jorie VersmissenDepartment of Hospital Pharmacy, Erasmus MC, University Medical Center Rotterdam, The Netherlands.ORCID 0000-0003-0674-7765
Floor van RosseDepartment of Hospital Pharmacy, Erasmus MC, University Medical Center Rotterdam, The Netherlands.ORCID 0000-0002-6194-3964

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medication safety is a cornerstone of patient care, yet traditional error-focused approaches often limit learning opportunities in healthcare. While Safety-I focuses on identifying the root cause of the problem, Safety-II adds the dimension of adaptability and resilience of health care professionals in complex environments. This paper describes an innovative educational intervention aimed at integrating Safety-II, the Functional Resonance Analysis Method (FRAM) and anticoagulation management into an existing medication safety course within the Erasmus University medical curriculum. The course, designed for master's-level medical students, uses Safety-II to analyze everyday clinical successes and to deepen understanding of anticoagulation processes in perioperative care. Students engage with clinical cases, create FRAM models, and reflect on their experiences during clerkships, which enhances their ability to recognize system strengths and adapt to complex situations. Teaching strategies such as 'flipped classroom' and 'just-in-time teaching' were incorporated, aligned with the medical curriculum, and enhanced active learning. Early implementation cycles led to iterative refinement of the course materials, informed by student and stakeholder feedback, as well as learning analytics. The course was successfully integrated into the medical curriculum, and our vision has since extended beyond the next generation of medical doctors. The Safety-II course has also been implemented into our cross-disciplinary education for healthcare professionals in specialist training. By integrating Safety-II thinking into various healthcare disciplines, we strive to contribute to a culture of safer, more resilient care, ensuring that adaptability and continuous learning are prioritized in all aspects of patient safety.

Indexed as

AnticoagulantsCurriculumPatient SafetyHumansNetherlandsAnticoagulants

Identifiers

PMID41971176
PMCPMC13068099

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.