Evidence map›Paper›PMID 41971091›Full record

ArticleFrontiers in pharmacology2026

From allergy to arrhythmia - electrophysiological basis for the antiarrhythmic properties of antazoline.

Felix Wiedmann, Anna Prodanova, Manuel Kraft, Frederike Marie Weitkamp, Amelie Paasche, Christian Goetz, Constanze Schmidt

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Felix Wiedmann *Department of Cardiology and Pneumology, University Medical Center Goettingen, Goettingen, Germany.
Anna Prodanova *Department of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Heidelberg, Germany.
Manuel KraftDepartment of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Heidelberg, Germany.
Frederike Marie WeitkampDepartment of Cardiology and Pneumology, University Medical Center Goettingen, Goettingen, Germany.
Amelie PaascheDepartment of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Heidelberg, Germany.
Christian GoetzDepartment of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Heidelberg, Germany.
Constanze SchmidtDepartment of Cardiology and Pneumology, University Medical Center Goettingen, Goettingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Antazoline, a first-generation H Methods: Electrophysiological measurements were performed using the two-electrode voltage clamp technique on 22 cardiac ion channels, expressed in Results: Antazoline strongly inhibited hERG (IC Discussion: Antazoline exhibits a distinct multichannel profile in a heterologous expression system, combining potent inhibition of hERG and hK

Indexed as

action potentialantazolineantiarrhythmic drugsatrial fibrillationmultichannel inhibitor

Identifiers

PMID41971091
PMCPMC13066279

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.