Evidence map›Paper›PMID 41971083›Full record

ReviewFrontiers in pharmacology2026

Tibetan medicine Baxiaga: a systematic review of its historical herbalogical investigation, phytochemical constituents, and pharmacological activities.

Nengqiao Fang, Hanyu Lu, Huimin Gao, Jing Ma, Renzhen Wangjia, Hang Chen, Jinsong Su, Yi Zhang

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nengqiao Fang *Chinese Medicine Germplasm Resources Innovation and Effective Uses Key Laboratory of Sichuan Province, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Hanyu Lu *Ethnic Medicine Academic Heritage Innovation Research Center/Meishan Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Huimin GaoState Key Laboratory of Southwestern Chinese Medicine Resources, Innovative Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Jing MaEthnic Medicine Academic Heritage Innovation Research Center/Meishan Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Renzhen WangjiaCollege of Pharmacy, Qinghai Minzu University, Xining, Qinghai, China.
Hang ChenGanzi Agricultural Sciences Institute, Ganzi, Sichuan, China.
Jinsong SuEthnic Medicine Academic Heritage Innovation Research Center/Meishan Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Yi ZhangEthnic Medicine Academic Heritage Innovation Research Center/Meishan Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Baxiaga (བ་ཤ་ཀ) is a typical Tibetan medicinal species of multiple origin. These plants have been used in traditional Tibetan medicine for centuries and are currently used to treat various types of fever, such as Chiba fever, liver fever, reduce inflammation, relieve pain, and heal other diseases. Objective: This review aims to provide a comprehensive analysis of the traditional uses of the baxiaga series of plants ( Materials and Methods: This review performed an extensive database search to collect detailed information about baxiaga and the literature was systematically interpreted, analyzed, and documented. Results: This review summarizes the traditional usage of five plants in Tibetan medicine baxiaga, which includes 195 chemical constituents such as alkaloids, flavonoids, terpenoids, and iridoid glycosides. This research elaborates on the pharmacological activities and mechanisms of these medicinal plants, along with discussions on multi-origin and quality control issues, while also proposing future research directions. Conclusion: This study presents a comprehensive analysis of the five medicinal plants commonly used in baxiaga. Our analysis highlights the significant value of baxiaga as an ethnomedicinal resource and reveals that its pharmacological activity is mainly attributed to its alkaloid. These alkaloids demonstrate anti-inflammatory, antioxidant and hepatoprotective, activities. However, current studies on the medicinal effects, active ingredient content, quality control, and clinical applications of baxiaga have limitations.

Indexed as

Baxiagapharmacological activitiesphytochemistryTibetan medicinetraditional medicinal uses

Identifiers

PMID41971083
PMCPMC13066925

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