Evidence map›Paper›PMID 41970997›Full record

ArticleFrontiers in endocrinology2026

Association between novel obesity- and lipid-related indices and diabetes across different FBG among elderly: a prospective cohort study.

Xiang-Yang He, Dong-Hui Ma, Zheng Liu, Yan-Fang Guo, Ren-Cheng Zhao, Pan-Pan Sun, Xing-Lin Zhong

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Xiang-Yang He *Department of Health Management, Shenzhen Baoan District Chronic Diseases Prevent and Cure Hospital, Shenzhen, Guangdong, China.
Dong-Hui Ma *Department of Endocrinology, The 987th Hospital of the PLA Joint Logistics Support Force, Baoji, Shaanxi, China.
Zheng LiuDepartment of Health Management, Shenzhen Baoan District Chronic Diseases Prevent and Cure Hospital, Shenzhen, Guangdong, China.
Yan-Fang GuoDepartment of Health Management, Shenzhen Baoan District Chronic Diseases Prevent and Cure Hospital, Shenzhen, Guangdong, China.
Ren-Cheng ZhaoDepartment of Health Management, Shenzhen Baoan District Chronic Diseases Prevent and Cure Hospital, Shenzhen, Guangdong, China.
Pan-Pan SunDepartment of Health Management, Shenzhen Baoan District Chronic Diseases Prevent and Cure Hospital, Shenzhen, Guangdong, China.
Xing-Lin ZhongMedical Department, Shenzhen University of Advanced Technology General Hospital, Shenzhen, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Although VAI, LAP, TyG and TyHGB are considered alternative indicators of abdominal fat deposition, their longitudinal association and strength of these indices with T2D remain unclear. The study aimed to evaluate the association between the indices and onset T2D in the elderly population across different FBG statuses and compare their predictive performance in risk assessment. Methods: Data were from the BaHLS, a cohort study of community-dwelling elderly individuals in Shenzhen, China. The study examined the associations between six novel obesity- and lipid-related indices (including BMI, WC, VAI, LAP, TyG and TyHGB) and the onset of T2D across different FBG statuses, including normal and elevated FBG. A multivariate Results: A total of 18,251 participants were enrolled in the study, with 1,350 (7.40%) participants were diagnosed with T2D by end of 2022. In the overall elderly cohort, the adjusted Conclusion: The study demonstrated that 6 obesity- and lipid- indices are positively associated with the incidence of onset T2D, and TyG and TyHGB demonstrated superior predictive performance for the onset of T2D in the elderly. Suggesting that TyG and TyHGB should be served as a valuable indicator for monitoring and preventing T2D.

Indexed as

Blood GlucoseDiabetes Mellitus, Type 2FastingHealth Status IndicatorsObesityAgedAged, 80 and overAging in PlaceArea Under CurveChinaFemaleFollow-Up StudiesHumansIncidenceLipidsLongitudinal StudiesBlood GlucoseLipidselderlylipid accumulation product (LAP)prospective cohort studytriglyceride glucose (TyG)triglyceride high-density cholesterol-glucose body (TyHGB)type 2 diabetes (T2D)visceral adiposity index (VAI)

Identifiers

PMID41970997
PMCPMC13063830

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.