ArticleFrontiers in endocrinology2026
Lipoprotein combined index and prevalent hyperuricemia among normolipidemic oilfield workers: a cross-sectional study.
Article in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Combined associations of tea consumption and smoking with accelerated biological aging among oilfield workers.Frontiers in nutrition · 2026Article
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12 authors.
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Abstract
Objectives: The lipoprotein combined index (LCI) reflects composite lipid metabolic patterns and may capture subtle metabolic disturbances beyond conventional lipid markers. Evidence regarding its relationship with hyperuricemia among normolipidemic individuals is scarce. This study investigated the association between LCI and hyperuricemia in an occupational population with normal lipid levels. Methods: A total of 2,029 normolipidemic oilfield workers were included. Hyperuricemia was primarily defined using sex-specific serum uric acid thresholds. Associations between LCI and hyperuricemia were examined using logistic regression, with dose-response relationships explored by restricted cubic spline (RCS) analysis. Prespecified subgroup and multiple sensitivity analyses were conducted to assess robustness. Results: Hyperuricemia prevalence rose from 9.25% in the lowest LCI quartile to 28.99% in the highest. In fully adjusted models, each standard deviation increase in LCI was associated with a 37% higher odds of hyperuricemia (OR = 1.37, 95% CI: 1.20-1.58, Conclusions: Higher LCI levels were associated with increased odds of hyperuricemia among normolipidemic oilfield workers. LCI may serve as an early marker of urate-related metabolic dysregulation, offering additional value beyond traditional lipid indicators. Longitudinal studies are warranted to confirm its predictive potential.
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