ArticleEndoscopy international open2026
Impact of acetic acid chromoendoscopy on detection of serrated lesions in the proximal colon compared with white-light endoscopy.
Article in Endoscopy international open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and study aims: Colorectal cancer (CRC) screening programs demonstrated a significant reduction in distal CRC mortality. However, similar results are not observed in proximal cancer, probably due to subtle and easily overlooked serrated lesions (SLs) that account for up to 30% of cases. Acetic acid chromoendoscopy may be useful in characterization of SLs. Data on its impact on SL detection rates remain limited. The aim of this study was to assess SL detection rates using high-definition white-light endoscopy (HD-WLE) versus sequential HD-WLE followed by 2% acetic acid chromoendoscopy (AAC) in the proximal colon and to evaluate the association between proximal SL rates and risk factors. Patients and methods: This prospective study included colonoscopies performed at a tertiary care center in patients aged ≥ 18 years between January and July 2021. HD-WLE was followed by HD-WLE with 2% acetic acid chromoendoscopy (AAC). SL detection rates were analyzed using McNemar's test, and risk factors were evaluated using multivariable logistic regression. Results: Four hundred thirty-four patients aged 18 to 82 years underwent both inspection strategies. Among proximal lesions, 60.9% were detected under HD-WLE and 39.1% after AAC ( Conclusions: HD-WLE with sequential application of 2% acetic acid chromoendoscopy was associated with higher proximal SL detection compared with HD-WLE alone. Hypertension was the only risk factor significantly associated with proximal SL detection, within the context of a sequential examination design.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.