Evidence map›Paper›PMID 41970608›Full record

ReviewParasite epidemiology and control2026

T cell exhaustion in

Williams Walana, Frank Yelevuuro Dasaa, Jennifer Suurbaar

Abstract readReview
In one paragraph

Review in Parasite epidemiology and control, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Williams WalanaUniversity for Development Studies, School of Medicine, Department of Clinical Microbiology, Tamale, Ghana.
Frank Yelevuuro DasaaUniversity for Development Studies, School of Medicine, Department of Clinical Microbiology, Tamale, Ghana.
Jennifer SuurbaarUniversity for Development Studies, School of Medicine, Department of Biochemistry and Molecular Medicine, Tamale, Ghana.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Giardiasis, caused by the protozoan parasite Objective: This review aims to synthesise existing literature on the relationship between T cell exhaustion and giardiasis, examine the T cell subsets affected, identify diagnostic markers that reflect the severity of Methodology: A comprehensive database search from Google Scholar and Medline/PubMed identified eligible studies that reported on T cell exhaustion markers, immune response and giardiasis. Search terms included "Giardia", "Giardiasis", "T cells" and "T cell exhaustion". Articles were reviewed for data on T-cell function, cytokine expression, and immune responses in people with giardiasis. Results: T cell exhaustion is common in giardiasis, as indicated by the findings. There are higher proliferation rates and upregulation of surface activation markers in CD4 cells in Conclusion: The activation and proliferation of T cells are key to the clearance of

Indexed as

G. DuodenalisGiardia intestinalisGiardia lambliaGiardiasisImmune exhaustionT cell exhaustion

Identifiers

PMID41970608
PMCPMC13068522

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.