Evidence map›Paper›PMID 41970579›Full record

ArticleBiomedical optics express2026

Tartrazine-enhanced visible-light OCT for deep-tissue imaging.

Jiaxuan Kong, Lingyun Wang, Shaohua Pi

Abstract read
In one paragraph

Article in Biomedical optics express, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jiaxuan KongDepartment of Ophthalmology, University of Pittsburgh, Pittsburgh, PA 15219, USA.ORCID https://orcid.org/0009-0003-1277-8768
Lingyun WangDepartment of Ophthalmology, University of Pittsburgh, Pittsburgh, PA 15219, USA.ORCID https://orcid.org/0000-0002-9380-6032
Shaohua PiDepartment of Ophthalmology, University of Pittsburgh, Pittsburgh, PA 15219, USA.ORCID https://orcid.org/0000-0002-7549-8929

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Visible-light optical coherence tomography (vis-OCT) provides ultrahigh axial resolution and intrinsic spectroscopic contrast, but its performance in deep tissues is fundamentally limited by strong scattering and absorption at short wavelengths. Here, we report the use of tartrazine-an FDA-approved, water-soluble food dye-as a rapid, biocompatible contrast enhancer to improve vis-OCT penetration and structural visibility across multiple tissue types. We systematically evaluated tartrazine-assisted imaging in postmortem chicken muscle, optic nerve, and brain cortex, as well as

Identifiers

PMID41970579
PMCPMC13064619

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.