ArticleFrontiers in medicine2026
Primary diffuse malignant epithelioid peritoneal mesothelioma of the greater omentum in an asbestos-naive patient: a case report.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Malignant mesothelioma is a rare malignant neoplasm of mesothelial origin, with primary involvement of the greater omentum being exceptionally uncommon. Nonspecific clinical manifestations often lead to misdiagnosis, and cases without asbestos exposure further increase diagnostic complexity. Case presentation: A 71-year-old male without asbestos exposure was admitted for recurrent diarrhea (>1 year), abdominal distension (>10 days), and unintentional weight loss (5 kg in 3 months). Physical examination revealed a 20-cm firm abdominal mass, and abdominal contrast-enhanced CT showed omental-peritoneal "cake-like" thickening with massive peritoneal effusion. Laparoscopic palliative tumor resection and peritoneal effusion drainage were performed, and postoperative pathology/immunohistochemistry (CK+, CR+, Conclusion: Definitive diagnosis of primary greater omental malignant mesothelioma relies on pathology and immunohistochemistry. For unresectable cases, palliative surgery combined with individualized adjuvant therapy may achieve favorable short-term outcomes, highlighting the need for early clinical suspicion in patients with unexplained abdominal symptoms.
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