Evidence map›Paper›PMID 41970377›Full record

Trial reportFrontiers in medicine2026

Effects of remimazolam on postanesthetic shivering and related clinical responses in patients undergoing cesarean section.

Ziyi Zhang, Minghong Liu, Qiang Zhang, Qingyu Wang, Liang Zhang, Hui Zhao, Yufeng Wang, Lili Li, Wenzhe Shen, Jun Shi

Abstract readClinical Trial
In one paragraph

Trial report in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ziyi ZhangGraduate School, Bengbu Medical University, Bengbu, China.
Minghong LiuDepartment of Anesthesiology, The First Affiliate Hospital of Anhui University of Science and Technology, Huainan, China.
Qiang ZhangGraduate School, Bengbu Medical University, Bengbu, China.
Qingyu WangGraduate School, Bengbu Medical University, Bengbu, China.
Liang ZhangGraduate School, Bengbu Medical University, Bengbu, China.
Hui ZhaoGraduate School, Bengbu Medical University, Bengbu, China.
Yufeng WangGraduate School, Bengbu Medical University, Bengbu, China.
Lili LiGraduate School, Bengbu Medical University, Bengbu, China.
Wenzhe ShenGraduate School, Bengbu Medical University, Bengbu, China.
Jun ShiDepartment of Anesthesiology, The First Affiliate Hospital of Anhui University of Science and Technology, Huainan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study aimed to evaluate the association between remimazolam administration and perioperative shivering as well as related clinical outcomes in patients undergoing cesarean section under neuraxial anesthesia. Methods: A total of 120 patients undergoing cesarean section under neuraxial anesthesia were randomly allocated to a remimazolam group (R), a remimazolam plus flumazenil group (RF), or a normal saline group (C) ( Results: The incidence of perioperative shivering was 17.5% in the R group and 30.0% in the RF group, both of which were significantly lower than that in the C group (52.5%; Conclusion: In patients undergoing cesarean section under neuraxial anesthesia, remimazolam administration after fetal delivery was associated with a lower incidence of perioperative shivering, higher perioperative body temperature, and reduced intraoperative traction responses. Differences in perioperative adverse events were observed among the groups. The reduction in perioperative shivering was partially preserved after reversal with flumazenil.

Indexed as

cesarean sectioncore body temperatureremimazolamshiveringspinal anesthesia

Identifiers

PMID41970377
PMCPMC13066202

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.