Evidence map›Paper›PMID 41970328›Full record

ArticleNutrition research and practice2026

Skim milk hydrolysate (SMH-AP) containing AVPYP and GLPQE ameliorates adipogenic lipid accumulation in 3T3-L1 cells.

Sekyung Lee, Hyung Joo Suh, Eun-Jin Jung, Hyeon-Son Choi

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Article in Nutrition research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sekyung LeeDepartment of Integrated Biomedical and Life Science, Graduate School, Korea University, Seoul 02841, Korea.ORCID https://orcid.org/0009-0001-5394-9653
Hyung Joo SuhDepartment of Integrated Biomedical and Life Science, Graduate School, Korea University, Seoul 02841, Korea.ORCID https://orcid.org/0000-0001-8869-3929
Eun-Jin JungDepartment of Food and Nutrition, Honam University, Gwangju 62399, Korea.ORCID https://orcid.org/0000-0002-2175-9345
Hyeon-Son ChoiDepartment of Food Nutrition, Sangmyung University, Seoul 03016, Korea.ORCID https://orcid.org/0000-0002-0165-7886

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesThis study evaluated the anti-adipogenic effects of skim milk hydrolysate with alcalase and prozyme (SMH-AP) in 3T3-L1 cells and identified its bioactive peptides. MATERIALS/

methodsAfter adipogenic differentiation, 3T3-L1 adipocytes were treated with SMH-AP.

resultsSMH-AP, produced via sequential hydrolysis with Alcalase and Prozyme, significantly inhibited lipid accumulation and modulated adipogenic and lipogenic biomarkers. It downregulated

conclusionThese findings suggest that SMH-AP may serve as a promising functional food ingredient for preventing obesity.

Indexed as

3T3-L1 cellsadipogenesisAVPYPlipid accumulationskim milk hydrolysate

Identifiers

PMID41970328
PMCPMC13062567

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.