Evidence map›Paper›PMID 41970280›Full record

ArticleTransplant international : official journal of the European Society for Organ Transplantation2026

Diagnostic Potential of Urine CXCL10 and Donor-Derived cfDNA in Kidney Transplant Rejection.

Daniel Fantus, Robert Balshaw, Chee Loong Saw, Majda Belkaid, Narin S Tangprasertchai, Thierry Viard, François Gougeon, Justin Belair, Claude Daniel, Caroline Lamarche and 3 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Transplant international : official journal of the European Society for Organ Transplantation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Daniel FantusDivision of Nephrology, Department of Medicine, Centre Hospitalier de l'Université de Montréal (CHUM), Montreal, QC, Canada.
Robert BalshawGeorge and Fay Yee Centre for Healthcare Innovation, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada.
Chee Loong SawHistocompatiblility and Immunogenetics Laboratory, McGill University Health Center (MUHC), Montreal, QC, Canada.
Majda BelkaidCentre de Recherche de CHUM (CRCHUM), Montreal, QC, Canada.
Narin S TangprasertchaiCareDx Inc., Brisbane, CA, United States.
Thierry ViardCareDx Inc., Brisbane, CA, United States.
François GougeonDepartment of Pathology and Cell Biology, Centre Hospitalier de l'Université de Montréal (CHUM), Montreal, QC, Canada.
Justin BelairCentre de Recherche de CHUM (CRCHUM), Montreal, QC, Canada.
Claude DanielHistocompatiblility and Immunogenetics Laboratory, McGill University Health Center (MUHC), Montreal, QC, Canada.
Caroline LamarcheDivision of Nephrology, Centre de Recherche de l'Hopital Maisonneuve-Rosemont, Montreal, QC, Canada.
Sílvia CasasCareDx Inc., Brisbane, CA, United States.
Heloise CardinalDivision of Nephrology, Department of Medicine, Centre Hospitalier de l'Université de Montréal (CHUM), Montreal, QC, Canada.
Julie HoDepartment of Internal Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Data suggests donor-derived cell-free DNA (dd-cfDNA) and urine CXCL10 outperform serum creatinine as a biomarker of antibody-mediated rejection (AMR) and T cell-mediated rejection (TCMR). We hypothesized that combining these biomarkers would improve the overall detection of rejection. We performed a retrospective two-center, case-controlled study of 103 adult renal transplant recipients who had for-cause or surveillance biopsies with corresponding urine and plasma samples. Rejection was classified by Banff 2022 criteria. While log

Indexed as

Cell-Free Nucleic AcidsChemokine CXCL10Graft RejectionKidney TransplantationAdultBiomarkersBiopsyCase-Control StudiesCreatinineFemaleHumansMaleMiddle AgedRetrospective StudiesTissue DonorsBiomarkersCell-Free Nucleic AcidsChemokine CXCL10CreatinineCXCL10 protein, humanCXCL10dd-cfDNAkidney transplantationnon-invasive immune monitoringrejection

Identifiers

PMID41970280
PMCPMC13067146

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.