Evidence map›Paper›PMID 41970251›Full record

ArticleMaterials today. Bio2026

Biomimetic bone calcium phosphate-based scaffolds fabricated via ceramic vat photopolymerization: Effect of porosity, sintering temperature, mineralogical phases and trace elements on the osteogenic potential.

Antonia Ressler, Roope Ohlsbom, Virginia Alessandra Gobbo, Markus Hannula, Katharina Keck, Harish Swaminathan, Toni-Karri Pakarinen, Mehdi Mohammadi, Jari Hyttinen, Jonathan Massera and 5 more

Erratum issuedAbstract read
In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Antonia ResslerFaculty of Engineering and Natural Sciences, Tampere University, Korkeakoulunkatu 6, P. O. Box 589, Tampere, 33014, Finland.
Roope OhlsbomFaculty of Medicine and Health Technology, Tampere University, Arvo Ylpön katu 34, Tampere, 33520, Finland.
Virginia Alessandra GobboFaculty of Engineering and Natural Sciences, Tampere University, Korkeakoulunkatu 6, P. O. Box 589, Tampere, 33014, Finland.
Markus HannulaFaculty of Medicine and Health Technology, Tampere University, Arvo Ylpön katu 34, Tampere, 33520, Finland.
Katharina KeckFaculty of Medicine and Health Technology, Tampere University, Arvo Ylpön katu 34, Tampere, 33520, Finland.
Harish SwaminathanFaculty of Engineering and Natural Sciences, Tampere University, Korkeakoulunkatu 6, P. O. Box 589, Tampere, 33014, Finland.
Toni-Karri PakarinenTampere University Hospital, Elämänaukio, Kuntokatu 2, Tampere, 33520, Finland.
Mehdi MohammadiLithoz GmbH, Mollardgasse 85a/2/64-69, Vienna, 1060, Austria.
Jari HyttinenFaculty of Medicine and Health Technology, Tampere University, Arvo Ylpön katu 34, Tampere, 33520, Finland.
Jonathan MasseraFaculty of Medicine and Health Technology, Tampere University, Arvo Ylpön katu 34, Tampere, 33520, Finland.
Martin SchwentenweinLithoz GmbH, Mollardgasse 85a/2/64-69, Vienna, 1060, Austria.
Erkka J FrankbergFaculty of Engineering and Natural Sciences, Tampere University, Korkeakoulunkatu 6, P. O. Box 589, Tampere, 33014, Finland.
Erkki LevänenFaculty of Engineering and Natural Sciences, Tampere University, Korkeakoulunkatu 6, P. O. Box 589, Tampere, 33014, Finland.
Arjen GebraadFaculty of Medicine and Health Technology, Tampere University, Arvo Ylpön katu 34, Tampere, 33520, Finland.
Susanna MiettinenFaculty of Medicine and Health Technology, Tampere University, Arvo Ylpön katu 34, Tampere, 33520, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In response to the growing demand for novel approaches in bone repair, scaffolds that mimic natural bone microstructure and mineralogical composition were developed using a ceramic vat photopolymerization (VPP) method. Due to varying reported results regarding appropriate microstructural characteristics, this study aimed to clarify the best pore size distribution and porosity among the tested scaffolds for an efficient osteogenic response. Scaffolds based on hydroxyapatite both support new bone formation by osteoblasts and can be resorbed by osteoclasts. An average pore size of ∼400 μm and porosity of 45.61% showed the best mechanical properties and osteogenic response, allowing cell penetration, and supporting cell-cell interactions and the differentiation process. When Sr,Mg,Zn-substituted hydroxyapatite is used for scaffold fabrication, the required high sintering temperatures lead to the transformation of hydroxyapatite into

Identifiers

PMID41970251
PMCPMC13068806

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.