Evidence map›Paper›PMID 41970234›Full record

ReviewFrontiers in chemistry2026

Exploration of covalent-organic frameworks and metal-organic frameworks for drug delivery applications.

Yuhao Sheng, Kunfang Ma

Abstract readReview
In one paragraph

Review in Frontiers in chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yuhao ShengSchool of Pharmacy, Nanjing Medical University, Nanjing, China.
Kunfang MaPharmaceutical Experiment Teaching Center, School of Pharmacy, Nanjing Medical University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Covalent-organic frameworks (COFs) and metal-organic frameworks (MOFs) have been a promising carrier for drug delivery because of excellent biocompatibility, developed porous structure and sufficient interactions of host-guest molecules. This paper mainly reviews latest research progress of COFs and MOFs including their synthesis approaches and applications in drug delivery. Specifically, COFs as drug carriers in chemotherapy, photodynamic therapy, photothermal therapy, synergistic therapy, anti-bacteria, and anti-inflammatory were systematically presented. MOFs in pharmaceutical drug delivery, controlled-release drug delivery, stimulus response and targeted drug delivery systems are introduced. The advantages and disadvantages of COFs and MOFs in synthesis and drug delivery performances was systematically compared. The future development trends of COFs and MOFs for drug delivery applications are discussed.

Indexed as

cancer therapycovalent-organic frameworksdelivery systemdrug carriermetal-organic frameworkssynthesis approach

Identifiers

PMID41970234
PMCPMC13066177

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.