Evidence map›Paper›PMID 41970228›Full record

ArticleRespiratory medicine case reports2026

Light Chain Deposition Disease - presenting with Cystic Pulmonary Disorder as primary manifestation - A case report.

M Krauss-Schilling, E H Fyllingen, A Jørgensen, M Raki, S Spetalen, S G F Wahl, T S Slørdahl, H Moaddab Hønnås, Ø Rasch-Halvorsen

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In one paragraph

Article in Respiratory medicine case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

M Krauss-SchillingDepartment of Thoracic and Occupational Medicine, St. Olavs Hospital - Trondheim University Hospital, Trondheim, Norway.
E H FyllingenDepartment of Radiology and Nuclear Medicine, St. Olavs Hospital - Trondheim University Hospital, Trondheim, Norway.
A JørgensenDepartment of Radiology and Nuclear Medicine, St. Olavs Hospital - Trondheim University Hospital, Trondheim, Norway.
M RakiDepartment of Pathology, Oslo University Hospital, Oslo, Norway and and Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
S SpetalenDepartment of Pathology, Oslo University Hospital, Oslo, Norway and and Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
S G F WahlDepartment of Pathology, St. Olavs Hospital - Trondheim University Hospital, Trondheim, Norway.
T S SlørdahlDepartment of Haematology, St. Olavs Hospital - Trondheim University Hospital, Trondheim, Norway.
H Moaddab HønnåsDepartment of Rheumatology, St. Olavs Hospital - Trondheim University Hospital, Trondheim, Norway.
Ø Rasch-HalvorsenDepartment of Thoracic and Occupational Medicine, St. Olavs Hospital - Trondheim University Hospital, Trondheim, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Light Chain Deposition Disease (LCDD) is a rare disease characterized by deposition of abnormal, non-amyloid, monoclonal light chains in tissues, potentially leading to organ dysfunction or failure. In most cases, LCDD occurs secondary to lymphoproliferative conditions, such as underlying B-cell disease. LCDD mainly affects the kidneys, liver and heart. Pulmonary LCDD (pLCDD) is less common, usually asymptomatic and acknowledged post-mortem. Furthermore, pLCDD exists in three forms i.e. an airway dominant, a nodular and a cystic form, which can all arise from a dominant B-cell clone restricted to the lung without multisystemic involvement. Herein we present a young man with isolated pLCDD manifested by cystic pulmonary involvement. Surgical lung wedge resection provided histological diagnostic confirmation showing extracellular deposits, which were negative by Congo red staining but positive for κ-light chain by immunohistochemistry and mass spectrometry. There was no sign of underlying hematological disease.

Indexed as

Case reportLight chain deposition diseaseLungRespiratory system

Identifiers

PMID41970228
PMCPMC13062529

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.