Evidence map›Paper›PMID 41970125›Full record

ArticleCureus2026

Fatal Interstitial Pneumonitis During Combined Degarelix, Darolutamide, and Docetaxel Therapy for Metastatic Prostate Cancer.

Fumihiro Ito, Koki Kobayashi, Gaku Hayashi, Shunsuke Kamijo, Takashi Fujita

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fumihiro ItoUrology, Gifu Prefectural Tajimi Hospital, Tajimi, JPN.
Koki KobayashiUrology, Gifu Prefectural Tajimi Hospital, Tajimi, JPN.
Gaku HayashiUrology, Gifu Prefectural Tajimi Hospital, Tajimi, JPN.
Shunsuke KamijoUrology, Gifu Prefectural Tajimi Hospital, Tajimi, JPN.
Takashi FujitaUrology, Gifu Prefectural Tajimi Hospital, Tajimi, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triplet therapy for metastatic hormone-sensitive prostate cancer improves survival but may rarely cause severe pulmonary toxicity. A 79-year-old man with low-volume metastatic prostate adenocarcinoma (PSA 613 ng/mL) received degarelix, darolutamide, and docetaxel. After the fifth docetaxel cycle, he developed a low-grade fever and exertional dyspnea. Chest computed tomography revealed diffuse, non-segmental bilateral ground-glass opacities. Microbiologic evaluation, including β-D-glucan and

Indexed as

androgen receptor targeted therapydocetaxel toxicitydrug-induced interstitial lung diseasefatal pulmonary toxicityinterstitial pneumonitismetastatic prostate cancertriplet therapy

Identifiers

PMID41970125
PMCPMC13063065

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.