Evidence map›Paper›PMID 41970121›Full record

ArticleCureus2026

Correlates of Maternal Iron Stores During Pregnancy and Cord Blood Ferritin Levels at Delivery in a Nigerian Tertiary Hospital.

Chimaobi Nwankpa, John Imaralu, Adebayo Akadri, John Sotunsa, Elizabeth Grillo, Victor C Okebalama, Adesola Adekoya, Ngozi Adefala, Odutola Odugbemi, Blessing Nwankpa and 6 more

Abstract read
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

16 authors.

Chimaobi NwankpaDepartment of Obstetrics and Gynaecology, Babcock University Teaching Hospital, Ilishan-Remo, NGA.
John ImaraluDepartment of Obstetrics and Gynaecology, Babcock University Teaching Hospital, Ilishan-Remo, NGA.
Adebayo AkadriDepartment of Obstetrics and Gynaecology, Babcock University Teaching Hospital, Ilishan-Remo, NGA.
John SotunsaDepartment of Obstetrics and Gynaecology, Babcock University Teaching Hospital, Ilishan-Remo, NGA.
Elizabeth GrilloDepartment of Obstetrics and Gynaecology, Babcock University Teaching Hospital, Ilishan-Remo, NGA.
Victor C OkebalamaDepartment of Histopathology, Babcock University Teaching Hospital, Ilishan-Remo, NGA.
Adesola AdekoyaDepartment of Paediatrics, Babcock University Teaching Hospital, Ilishan-Remo, NGA.
Ngozi AdefalaDepartment of Community Medicine, Babcock University Teaching Hospital, Ilishan-Remo, NGA.
Odutola OdugbemiDepartment of Obstetrics and Gynaecology, Babcock University Teaching Hospital, Ilishan-Remo, NGA.
Blessing NwankpaDepartment of Obstetrics and Gynaecology, Manchester University NHS Foundation Trust, Manchester, GBR.
Oluwuyiwa AdelowoDepartment of Obstetrics and Gynaecology, Babcock University Teaching Hospital, Ilishan-Remo, NGA.
Nneoma Obinna-ChinatuDepartment of Paediatrics, Royal Stoke University Hospital, University Hospitals of North Midlands NHS Trust, Stoke, GBR.
Rukayat OlayemiDepartment of Obstetrics and Gynaecology, Crescent University, Abeokuta, NGA.
Oluyemisi OkwudishuDepartment of Internal Medicine, Babcock University Teaching Hospital, Ilishan-Remo, NGA.
Ekeleoma ObasiDepartment of General Medicine, Royal Care Specialist Hospital, Abuja, NGA.
Ugochukwu ChigozieDepartment of Paediatrics, Babcock University Teaching Hospital, Ilishan-Remo, NGA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInsufficient iron is a common nutritional deficiency globally. It is a significant cause of anemia in pregnancy and a common problem in obstetric care due to the increased demand for iron by the developing fetus and placenta. It has been associated with adverse maternal and perinatal outcomes. To maintain iron balance, maternal iron stores before and during pregnancy have been suggested to be an indispensable factor. However, there is no consensus on the effect of iron stores in mothers on neonatal iron stores.

aimTo establish the relationship between maternal iron stores in pregnancy and cord ferritin at delivery, birth weight, placenta weight, and Apgar scores. METHODOLOGY: This study included 170 mothers and neonatal pairs. Maternal venous blood was obtained in labor, while 5 ml of cord blood was collected soon after childbirth for ferritin and hemoglobin assay using enzyme-linked immunosorbent assay (ELISA) and a hemoglobinometer, respectively. Sociodemographic details, birth weight, placenta weight, and Apgar scores were obtained. IBM SPSS version 22 (IBM Corp., Armonk, NY) was employed to carry out the statistical data analysis.

resultThe prevalence of iron deficiency was 27.6% (47). The mean maternal ferritin concentration was 23.9 ± 19.8 ng/ml. The mean cord ferritin was 223 ± 234 ng/ml. There was no relationship between maternal ferritin levels and cord ferritin (r = 0.002, p = 0.981), cord hemoglobin, placenta weight, birth weight, and Apgar score. Cord ferritin and cord hemoglobin showed a negative correlation (r = -0.222, P = 0.004). The mean hemoglobin level (14.3 ± 1.9) was significantly higher in neonates with lower ferritin (t = 2.960, p = 0.004). Apgar scores at one and five minutes were significantly lower in neonates with low cord blood ferritin compared to neonates having normal blood ferritin (at one minute: 7 ± 1 vs. 8 ± 1, p = 0.039; at five minutes: 9 ± 1 vs. 10 ± 1, p = 0.011).

conclusionMaternal iron stores and neonatal iron stores showed no relationship between them at delivery. The inverse relationship between cord ferritin and neonatal hemoglobin suggests that some unexplained factors may be responsible for this, which warrants further research. Furthermore, adequate iron stores influenced better neonatal outcomes.

Indexed as

apgar scorebirth weightcord ferritindeliveryiron storesplacenta weightpregnancyrelationship

Identifiers

PMID41970121
PMCPMC13068304

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.