ReviewCureus2026
Nickel-Titanium Alloys in Endodontics: A Narrative Review.
Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The introduction of nickel-titanium (NiTi) rotary instruments has profoundly transformed modern endodontics, enabling safer and more conservative shaping of complex root canal systems. Despite technological advances, unexpected instrument fracture remains a relevant clinical concern, highlighting the importance of understanding the metallurgical and biomechanical mechanisms governing instrument behavior. This review aims to critically analyze the metallurgical evolution, biomechanical performance, and clinical implications of NiTi instruments, with particular emphasis on heat-treated alloys, phase transformations, shaping kinematics, and stress management during canal preparation. A non-systematic narrative review methodology was adopted. Relevant scientific literature addressing NiTi metallurgy, cyclic fatigue resistance, torsional stress, corrosion phenomena, glide path preparation, and rotary versus reciprocating kinematics was analyzed, integrating experimental, metallurgical, and clinical studies selected for their conceptual relevance to contemporary endodontic practice. The clinical performance of NiTi instruments results from the interaction between alloy metallurgy, geometric design, and operative protocols. Thermomechanical treatments increase martensitic phase presence at clinical temperatures, enhancing flexibility and cyclic fatigue resistance. However, surface defects, corrosive environments, and stress accumulation remain critical factors in instrument failure mechanisms, indicating that material properties alone do not determine clinical safety. Contemporary root canal shaping should be interpreted as a biomechanical stress management process rather than simple canal enlargement. Integration of metallurgical knowledge with operative strategies represents a fundamental prerequisite for safer and biologically conservative endodontic treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.