ArticleFrontiers in neurology
Correlation between MRI high-signal parameters and prognosis in cervical spinal cord injury without fracture and dislocation.
Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: Although patients with cervical spinal cord injury without fracture and dislocation (CSCIwoFD) often exhibit increased signal intensity (ISI) on magnetic resonance imaging (MRI), the prognostic significance of these changes has not been clearly established. This study retrospectively analyzed 118 patients with confirmed CSCIwoFD to examine the relationship between MRI-derived ISI parameters and the recovery rate of Japanese Orthopaedic Association (JOA) scores, in order to evaluate their predictive value for functional outcomes and disease severity. Methods: A retrospective analysis was conducted on 118 patients diagnosed with cervical spinal cord injury without fracture and dislocation (CSCIwoFD) who underwent surgical treatment at our hospital between August 2020 and June 2024. MRI scans at admission showing high signal intensity changes on axial and sagittal planes were analyzed. Two attending physicians independently measured and recorded the following parameters according to a standardized protocol: Axial values: maximum signal intensity (A Results: All 118 patients successfully underwent surgery. The follow-up period ranged from 12 to 33 months. The mean preoperative JOA score was 8.58 ± 3.02 points. At 3 months postoperatively, the mean JOA score was 13.16 ± 2.22 points, with an average recovery rate of 49.42 ± 23.82%. At 2 years postoperatively, the mean JOA score increased to 15.11 ± 1.53 points, with an average recovery rate of 70.11 ± 28.48%, indicating a definitive therapeutic effect of surgery. When "good recovery at 3 months postoperatively" was used as the grouping variable, the results showed that the ASDR was significantly associated with good recovery ( Conclusion: This study provides valuable insights into the utility of routine MRI sequences for evaluating CSCIwoFD. The ASDR demonstrated moderate predictive efficacy as a single-variable parameter and may serve as a sensitive screening indicator for early postoperative neurological improvement. Its incorporation into prognostic assessment could offer clinically relevant information and support decision-making. We therefore recommend considering this ratio as a core variable in the construction of early postoperative prognostic models.
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