ArticleJB & JS open access
Risk Factors for Discordance Between Synovial Fluid Culture and Intraoperative Cultures in Revision Arthroplasties: Results From a European Multicentre Observational Study.
Article in JB & JS open access. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
18 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Isolating the causative microorganism in patients with a periprosthetic joint infection (PJI) before revision surgery is critical to determine the right surgical and antibiotic strategy. A wide variety in concordance between p-SFC and intraoperative cultures is reported in the literature.The objective was to determine the incidence of discordance and analyze risk factors for discordance between a positive preoperative synovial culture and intraoperative cultures in revision arthroplasty for PJI. Method: An international multicenter retrospective observational cohort study was conducted including patients with septic total revision arthroplasty, between January 2020 and January 2024. Discordance and risk factors were analyzed. Results: Discordance was 36% (n = 647). Risk factors for discordance were center specific: OR 4.22 (95% confidence interval [CI] 2.97-5.99), the presence of a sinus tract: odds ratio (OR) 1.80 (95% CI 1.22-2.66), and the hip joint: OR 1.61 (95% CI 1.12-2.30). Conclusion: Discordance between positive preoperative synovial fluid culture and intraoperative cultures in revision arthroplasty is relatively high, center-specific, and less reliable in patients with hip arthroplasty and/or a sinus tract.
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