Relationship between metabolic dysfunction-associated steatotic liver disease and sleep disorders: an umbrella review.

Yuanfei Wang, Wanyi Ou, Ling Zhu

Abstract readReview

In one paragraph

Review in Sleep and biological rhythms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yuanfei Wang *Nursing Department, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.

Wanyi Ou *School of Nursing, Jinan University, Guangzhou, China.

Ling ZhuNursing Department, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Umbrella review, also known as a systematic review of systematic reviews, is positioned at the apex of the evidence-based medicine pyramid and represents one of the highest levels of methodology for evidence synthesis. This umbrella review evaluates the current body of evidence linking sleep disorders with metabolic dysfunction-associated steatotic liver disease (MASLD), in light of growing indications that disturbances in sleep may play a role in the development and progression of MASLD. Following PRISMA framework, a systematic literature search was performed across five databases (PubMed, Web of Science, Embase, CNKI, and Wanfang Data) from inception to April 2025. Eligible studies examined the relationship between sleep disorders and MASLD. Twenty studies (seventeen quantitative, three qualitative) were included. Key findings revealed: (1) Short sleep duration and obstructive sleep apnea (OSA) were significantly associated with increased MASLD risk ( Supplementary Information: The online version contains supplementary material available at 10.1007/s41105-026-00636-w.

Indexed as

Fatty liver diseaseSleep disruptionUmbrella review

Identifiers

PMID41969987

DOI10.1007/s41105-026-00636-w

PMCPMC13065926

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.