ArticleGland surgery2026
Shear wave elastography combined with fine-needle aspiration biopsy in the diagnosis of China Thyroid Imaging Reporting and Data System category 4 thyroid nodules.
Article in Gland surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Shear wave elastography (SWE) and fine-needle aspiration biopsy (FNAB) are both effective methods for diagnosing thyroid nodules. This study aimed to evaluate the efficiency of SWE combined with FNAB for the diagnosis of China Thyroid Imaging Reporting and Data System (C-TIRADS) category 4 thyroid nodules. Methods: The FNAB results and images from conventional ultrasound and SWE of 209 C-TIRADS category 4 thyroid nodules that were confirmed by postoperative pathology from July 2021 to July 2024 were retrospectively analyzed. The diagnostic efficiency of SWE, FNAB, and their combination were assess and compared. Results: The receiver operating characteristic (ROC) curve showed the best cutoff value for the SWE maximum elastic modulus of thyroid nodules was 42.65 kPa, yielding an area under the ROC curve (AUC) of 0.823 [95% confidence interval (CI): 0.765-0.880]; meanwhile, the sensitivity, specificity, accuracy were 75.2% (115/153), 78.6% (44/56), and 76.1% (159/209), respectively. FNAB identified 42 benign nodules, 59 indeterminate ones (Bethesda categories III, IV, and V), and 108 malignant ones; meanwhile, the diagnostic sensitivity, specificity, accuracy were 70.6% (108/153), 71.4% (40/56), and 70.8% (148/209), respectively. After SWE was combined with FNAB, 68 and 141 nodules were identified as negative and positive, respectively, and the sensitivity, specificity, accuracy were 92.2% (141/153), 100% (56/56), and 94.3% (197/209), respectively, representing a significant improvement in all three metrics (all P values <0.001). Conclusions: SWE and FNAB had reliable diagnostic efficiency for C-TIRADS category 4 thyroid nodules, and their combination had greater sensitivity, specificity, and accuracy, thus supporting their clinical value.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.