ArticleGland surgery2026
The impact of early exercise intervention on the incidence and severity of lymphedema following axillary lymph node dissection in breast cancer.
Article in Gland surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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6 authors.
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Abstract
Background: Breast cancer-related lymphedema (BCRL) is a chronic complication of axillary lymph node dissection (ALND) that impairs mobility and quality of life (QoL). This study evaluated the impact of early systematic exercise on BCRL incidence, severity, and functional recovery. Methods: A retrospective cohort study analyzed 136 patients who underwent ALND between 2020 and 2024. The intervention group (n=70) participated in a therapist-guided, phased exercise program initiated within two weeks post-surgery. The control group (n=66) received conventional health education. The primary outcome was BCRL incidence within 12 months (defined as ≥10% or ≥200 mL volume increase). Secondary outcomes included shoulder range of motion (ROM), [Disabilities of the Arm, Shoulder, and Hand (DASH) score] scores, pain [Visual Analog Scale (VAS) score], and QoL [European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 and breast cancer module (EORTC QLQ-C30/BR23)]. Results: The overall BCRL incidence was 25.0%. The intervention group showed a significantly lower incidence compared to controls (17.1% Conclusions: Early, systematic exercise intervention after ALND is a safe and effective strategy to reduce BCRL risk and severity. It significantly enhances physical function and QoL, particularly in high-risk populations. These findings support integrating individualized exercise programs into routine postoperative rehabilitation pathways.
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