Evidence map›Paper›PMID 41969906›Full record

ArticleFrontiers in psychology2026

Investigating the functional neural network dynamics of cognitive-affective action planning during threat processing.

John Foley, Siraj J Lyons, Olivia Cook, Brendan E Depue

Abstract read
In one paragraph

Article in Frontiers in psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

John FoleyDepartment of Psychological & Brain Sciences, University of Louisville, Louisville, KY, United States.
Siraj J LyonsDepartment of Psychological & Brain Sciences, University of Louisville, Louisville, KY, United States.
Olivia CookDepartment of Psychological & Brain Sciences, University of Louisville, Louisville, KY, United States.
Brendan E DepueDepartment of Psychological & Brain Sciences, University of Louisville, Louisville, KY, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The current investigation used functional neuroimaging data from four different tasks involving threatening/fearful faces and screams to understand the functional organization of neural networks. Methods: Emphasis was placed on graph theory metrics of both local connectivity (participation coefficient, betweenness centrality) and global connectivity (global efficiency, modularity) to assess intra- and inter-network connectivity across a highly parcellated (412 nodes) brain template. A total of 124 participants (57% female; Results: Our findings suggest that a diffuse pattern of strengthened intra-network connectivity defined social threat processing. Univariate analyses exhibited a preponderance of nodes within the somatomotor network, indicating the potential for motor preparation during social threat processing. Multivariate classification exhibited more diffuse focal participation from limbic, default, visual, attentional, control and somatomotor ICNs. Conclusion: Our results suggest the role of intra- and inter-network functional organization in response to threat and carries implications for viewing various networks through dynamic perspectives.

Indexed as

emotionfMRIfunctional connectivityneural networkthreat

Identifiers

PMID41969906
PMCPMC13065709

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.