Evidence map›Paper›PMID 41969832›Full record

ArticleNorth American Spine Society journal2026

Chronic opioid prescription rates following long-segment lumbar instrumentation: A comparison of academic and nonacademic centers.

Janesh Karnati, Sruthi Ranganathan, Xu Tao, Aydin Kaghazchi, Shameel Abid, Andrew Wu, Ahmed Ashraf, Gabriel Jelkin, Leina Lunasco, Sachin Shankar and 3 more

Abstract read
In one paragraph

Article in North American Spine Society journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Janesh KarnatiDepartment of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, OH, United States.
Sruthi RanganathanDepartment of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, OH, United States.
Xu TaoDepartment of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, OH, United States.
Aydin KaghazchiDepartment of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, OH, United States.
Shameel AbidDepartment of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, OH, United States.
Andrew WuDepartment of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, OH, United States.
Ahmed AshrafDepartment of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, OH, United States.
Gabriel JelkinDepartment of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, OH, United States.
Leina LunascoDepartment of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, OH, United States.
Sachin ShankarDepartment of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, OH, United States.
Mikayla WallaceDepartment of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, OH, United States.
Joseph ChengDepartment of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, OH, United States.
Owoicho AdogwaDepartment of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, OH, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Postoperative opioid prescribing after spine surgery varies widely, and institutional factors such as academic center status may influence long-term opioid use. Understanding these differences is important for improving opioid stewardship following complex lumbar procedures. Methods: A retrospective cohort study using the TriNetX Research Network evaluated chronic postoperative opioid prescribing after long-segment posterior lumbar instrumentation. Patients undergoing posterior lumbar instrumentation spanning 3 to 12 vertebral segments between 2010 and 2022 were stratified by treatment at academic or nonacademic centers. Propensity score matching balanced cohorts for demographics, comorbidities, and preoperative analgesic use. Opioid prescriptions were assessed at 3 to 6 months, 6 to 12 months, and 12 to 24 months postoperatively and categorized by metabolic class and strength. Logistic regression compared postoperative opioid prescribing between cohorts. Results: After propensity score matching, 7,883 patients were included in each cohort. At 3 to 6 months postoperatively, patients treated at nonacademic centers had lower odds of receiving opioids compared to those treated at academic centers, including lower odds of codeine-based opioids (OR: 0.77, 95% CI: 0.71-0.82) and weak opioids (OR: 0.71, 95% CI: 0.63-0.79). At 6 to 12 months, patients at nonacademic centers demonstrated higher odds of receiving non-codeine-based opioids (OR: 1.20, 95% CI: 1.10-1.31). At 12 to 24 months postoperatively, treatment at nonacademic centers was associated with higher odds of non-codeine-based opioids (OR: 1.26, 95% CI: 1.17-1.36), strong opioids (OR: 1.17, 95% CI: 1.08-1.25), and moderate opioids (OR: 1.11, 95% CI: 1.02-1.21). Conclusions: Postoperative opioid prescribing following long-segment lumbar instrumentation differs between academic and nonacademic centers and varies over time. These findings highlight institutional variation in long-term opioid prescribing and underscore the need for further studies to identify drivers of these differences and optimize postoperative pain management strategies.

Indexed as

AcademicChronic OpioidsLumbar SurgeryOpioidsPostoperative complicationsSpinal instrumentation

Identifiers

PMID41969832
PMCPMC13068836

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.