ArticleThe Journal of innovations in cardiac rhythm management2026
Flecainide Provides Comparable Rhythm Control Efficacy to Repeat Radiofrequency Ablation in Patients with Paroxysmal Atrial Fibrillation After Failed Cryoballoon Ablation.
Article in The Journal of innovations in cardiac rhythm management, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
- Letter from the Editor in Chief.The Journal of innovations in cardiac rhythm management · 2026Article
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6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Class IC anti-arrhythmic drugs are primarily preferred for the rhythm control of atrial fibrillation (AF). In cases where ablation fails, the appropriate rhythm-control strategy is still unclear. In our study, we aimed to evaluate the efficacy of flecainide, propafenone, and radiofrequency ablation (RFA) as rhythm-control strategies in paroxysmal AF patients with failed cryoballoon ablation (CBA). In this cross-sectional study, 1120 patients who underwent CBA for paroxysmal AF between 2017 and 2024 were screened. Within this patient group, 230 patients with recurrent AF (≥3 months) after CBA were identified. A total of 120 patients (40 cases per treatment) who underwent rhythm control and received flecainide, propafenone, or RFA were finally included in the study. Study participants were then divided into three groups, receiving flecainide (group I), propafenone (group II), or RFA (group III). All patients were followed up for at least 1 year for AF recurrence, which was confirmed in 52 (43.2%) patients. The AF recurrence rates in groups I, II, and III were 35%, 75%, and 20%, respectively. Although the frequency of AF recurrence in groups I and III was statistically similar (
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