ArticleResearch and practice in thrombosis and haemostasis2026
Impact of adherence to elastic compression stockings on efficacy to prevent postthrombotic syndrome: a prespecified analysis of the Compression Elastique Evaluation du Syndrome post Thrombotique study.
Article in Research and practice in thrombosis and haemostasis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Elastic compression stockings (ECS) are commonly used to prevent postthrombotic syndrome (PTS) after deep vein thrombosis (DVT). However, their efficacy is controversial. This could be due to suboptimal adherence in the negative study. Additional data on the impact of adherence on ECS efficacy are needed. Objectives: To assess the impact of adherence on ECS efficacy to prevent PTS. Methods: We conducted a prespecified analysis of the double-blind "Compression Elastique Evaluation du Syndrome post Thrombotique" trial comparing 25 mm Hg ECS with 35 mm Hg ECS to prevent PTS after DVT. The objectives were to 1) assess the proportion of patients with PTS at 2 years according to adherence to ECS; 2) assess predictors of PTS; and 3) build a decision tree algorithm to measure the impact of each independent predictor of PTS. Results: The proportion of patients with PTS at 2 years who whore the study ECS <50%, 50% to 79%, and Conclusion: Adherence to ECS is an independent predictor of PTS that becomes apparent when ECS are worn
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